Schrijen-Floor Jacqueline M, Fennis Willem M M, Abbink Jan H, de Putter Cornelis, Koole Ronald, van den Braber Willem
Int J Prosthodont. 2015 May-Jun;28(3):252-7. doi: 10.11607/ijp.4097.
This study aimed to investigate the impact of preradiation tooth loss in patients with head and neck cancer.
Records of 397 (partially) dentate patients who were referred for preradiation oral screening were included. Number and location of teeth lost and occluding pairs lost were determined for different tumor locations.
The majority of patients (54%) were affected by tooth loss. Proportion of teeth lost, their location, and proportion of occluding pairs lost were not evenly distributed across tumor locations. The highest proportions of teeth were removed with oral tumors (maxilla: 25%; mandible: 47%). For preradiation preventive extractions only, ie, not taking into account teeth that were lost due to ablative surgery, tooth loss in the mandible was still not evenly distributed across tumor locations, but tooth loss in the maxilla and occluding pairs lost were.
Tumor location affects preradiation tooth loss, though this is primarily a consequence of ablative surgery rather than a consequence of preradiation dental extraction decisions. Since patients with oral cavity tumors are affected most by preradiation tooth loss, treatment planning with regard to functional rehabilitation is desirable for this patient group in particular.
本研究旨在调查头颈部癌患者放疗前牙齿缺失的影响。
纳入397例接受放疗前口腔筛查的（部分）有牙患者的记录。确定不同肿瘤部位牙齿缺失的数量和位置以及咬合对缺失的情况。
大多数患者（54%）存在牙齿缺失。牙齿缺失的比例、位置以及咬合对缺失的比例在不同肿瘤部位分布不均。口腔肿瘤患者牙齿拔除比例最高（上颌：25%；下颌：47%）。仅考虑放疗前预防性拔牙，即不考虑因消融手术导致的牙齿缺失，下颌牙齿缺失在不同肿瘤部位仍分布不均，但上颌牙齿缺失和咬合对缺失的情况分布均匀。
肿瘤部位影响放疗前牙齿缺失，不过这主要是消融手术的结果，而非放疗前拔牙决策的结果。由于口腔肿瘤患者受放疗前牙齿缺失影响最大，因此尤其需要针对该患者群体进行功能康复方面的治疗规划。
