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癫痫病房中的心脏停搏。

Asystole in the epilepsy unit.

作者信息

Honig Asaf, Chen Shmuel, Benninger Felix, Bar-Yossef Rima, Eichel Roni, Kipervasser Svetlana, Blatt Ilan, Neufeld Miri Y, Ekstein Dana

机构信息

Department of Neurology, the Agnes Ginges Center of Neurogenetics, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Department of Cardiology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

出版信息

BMC Neurol. 2015 May 14;15:80. doi: 10.1186/s12883-015-0336-y.

DOI:10.1186/s12883-015-0336-y
PMID:25966854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4464125/
Abstract

BACKGROUND

Early identification of cardiac asystole as a reason for syncope is of uttermost significance, as insertion of a cardiac pacemaker can save the patient's life and prevent severe injury. The aim of this work was to emphasize the subtle and unusual presentations of asystole in patients evaluated in epilepsy units.

METHODS

We reviewed the clinical presentation, ECG and EEG data of a series of seven patients who were evaluated in four epilepsy units and were diagnosed with asystole.

RESULTS

Three patients had unusual clinical manifestations of cardiac asystole, resembling epileptic seizures. Three patients had asystole induced by epileptic seizures and in one patient the diagnosis was not clear. All patients except one were implanted with a pacemaker and improved clinically.

CONCLUSIONS

Seizure-induced asystole is a rare complication of epilepsy and asystole may clinically mimic epileptic seizures. A high level of suspicion and thorough prolonged cardiac and EEG monitoring are mandatory for reaching the right diagnosis. As the diagnosis is rare and difficult to reach, a flow chart to assist diagnosis is suggested.

摘要

背景

早期识别心脏停搏作为晕厥的原因至关重要,因为植入心脏起搏器可挽救患者生命并防止严重损伤。这项工作的目的是强调在癫痫单元接受评估的患者中,心脏停搏的细微和不寻常表现。

方法

我们回顾了在四个癫痫单元接受评估并被诊断为心脏停搏的一系列七名患者的临床表现、心电图和脑电图数据。

结果

三名患者有心脏停搏的不寻常临床表现,类似于癫痫发作。三名患者因癫痫发作诱发心脏停搏,一名患者的诊断不明确。除一名患者外,所有患者均植入了起搏器,临床症状有所改善。

结论

癫痫发作诱发的心脏停搏是癫痫的一种罕见并发症,心脏停搏在临床上可能模仿癫痫发作。高度怀疑并进行全面、长时间的心脏和脑电图监测对于做出正确诊断是必不可少的。由于这种诊断罕见且难以做出,建议使用一个辅助诊断的流程图。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b143/4464125/bd661654b78e/12883_2015_336_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b143/4464125/2074452d8def/12883_2015_336_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b143/4464125/bd661654b78e/12883_2015_336_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b143/4464125/2074452d8def/12883_2015_336_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b143/4464125/bd661654b78e/12883_2015_336_Fig2_HTML.jpg

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本文引用的文献

1
CNS-disease affecting the heart: brain-heart disorders.影响心脏的中枢神经系统疾病:脑心疾病。
J Neurol Sci. 2014 Oct 15;345(1-2):8-14. doi: 10.1016/j.jns.2014.07.003. Epub 2014 Jul 8.
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Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention.癫痫性猝死的机制:预防途径
Nat Rev Neurol. 2014 May;10(5):271-82. doi: 10.1038/nrneurol.2014.64. Epub 2014 Apr 22.
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Syncope, seizure-induced bradycardia and asystole: two cases and review of clinical and pathophysiological features.晕厥、癫痫诱发的心动过缓和心搏停止:两例病例及临床和病理生理特征综述
Seizure. 2014 Aug;23(7):506-11. doi: 10.1016/j.seizure.2014.03.004. Epub 2014 Mar 12.
4
Characterization of seizure-induced syncopes: EEG, ECG, and clinical features.癫痫发作引起的晕厥的特征:脑电图、心电图和临床特征。
Epilepsia. 2014 Jan;55(1):146-55. doi: 10.1111/epi.12482. Epub 2013 Dec 20.
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Syncope.晕厥
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Common imitators of epilepsy.
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The treatment of ictal asystole with cardiac pacing.癫痫性心搏停止的起搏治疗。
Epilepsia. 2011 Apr;52(4):e16-9. doi: 10.1111/j.1528-1167.2010.02972.x. Epub 2011 Feb 14.
8
Management and long-term outcome in patients presenting with ictal asystole or bradycardia.发作性心搏停止或心动过缓患者的管理和长期预后。
Epilepsia. 2011 Jun;52(6):1160-7. doi: 10.1111/j.1528-1167.2010.02961.x. Epub 2011 Feb 14.
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Seizure induced cardiac asystole in epilepsy patients undergoing long term video-EEG monitoring.癫痫患者在接受长期视频脑电图监测时发生的癫痫相关性心搏停止。
Seizure. 2011 Mar;20(2):167-72. doi: 10.1016/j.seizure.2010.11.017. Epub 2010 Dec 22.
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Recurrent unexplained syncope may have a cerebral origin: report of 10 cases of arrhythmogenic epilepsy.复发性不明原因晕厥可能源于脑部:10例致心律失常性癫痫的报告
Arch Cardiovasc Dis. 2009 May;102(5):397-407. doi: 10.1016/j.acvd.2009.02.014. Epub 2009 Apr 29.