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5-Chloro-2-phenyl-1-benzo[b]thiophene-3-alkanimines, potential antipsychotic agents.

作者信息

Kukla M J, Woo C M, Kehr J R, Miller A

出版信息

J Med Chem. 1978 Apr;21(4):348-52. doi: 10.1021/jm00202a007.

Abstract

The title compounds (most notably 2a) were synthesized on the basis of the N-methylation hypothesis of schizophrenia. They were evaluated in dopamine and haloperidol receptor assays. The binding characteristics were comparable in some cases to known neuroleptics.

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