Kukla M J, Woo C M, Kehr J R, Miller A
J Med Chem. 1978 Apr;21(4):348-52. doi: 10.1021/jm00202a007.
The title compounds (most notably 2a) were synthesized on the basis of the N-methylation hypothesis of schizophrenia. They were evaluated in dopamine and haloperidol receptor assays. The binding characteristics were comparable in some cases to known neuroleptics.