Fernandez-Prada Sara, Delgado-Sanchez Elsa, De Santiago Javier, Zapardiel Ignacio
Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
J Minim Invasive Gynecol. 2015 Sep-Oct;22(6):1075-8. doi: 10.1016/j.jmig.2015.05.002. Epub 2015 May 9.
In endometrial cancer, the histopathological analysis of the lymphatic nodes is essential to establish a correct prognosis and tailored adjuvant treatment. It is well-known that patients with early-stage endometrial cancer have a low incidence of nodal disease. In this group, systematic lymphadenectomy is not recommended. To improve the detection rate of sentinel nodes in clinical practice, new techniques are emerging like real-time 3-dimensional single-photon emission computed tomographic (SPECT) imaging. We report our experience using this innovative technique for intraoperative detection of sentinel nodes in endometrial cancer. The real-time 3-dimensional SPECT sentinel node biopsy seems to be feasible and accurate in endometrial cancer although further studies are needed to set the precision and predictive values compared with the current differed SPECT techniques and blue dye techniques.
在子宫内膜癌中，淋巴结的组织病理学分析对于确立正确的预后及制定个体化辅助治疗至关重要。众所周知，早期子宫内膜癌患者发生淋巴结转移的几率较低。对于这一群体，不建议进行系统性淋巴结清扫术。为提高临床实践中前哨淋巴结的检出率，诸如实时三维单光子发射计算机断层扫描（SPECT）成像等新技术不断涌现。我们报告了使用这种创新技术在子宫内膜癌术中检测前哨淋巴结的经验。实时三维SPECT前哨淋巴结活检在子宫内膜癌中似乎是可行且准确的，不过与当前不同的SPECT技术及蓝色染料技术相比，仍需进一步研究来确定其精确性和预测价值。
