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老年人原发性失眠:非药物治疗

Insomnia (primary) in older people: non-drug treatments.

作者信息

Alessi Cathy, Vitiello Michael V

机构信息

Veterans Administration Greater Los Angeles Healthcare System, David Geffen School of Medicine at UCLA, Los Angeles, US.

出版信息

BMJ Clin Evid. 2015 May 13;2015:2302.

Abstract

INTRODUCTION

Up to 40% of older adults have insomnia, with difficulty getting to sleep, early waking, or feeling unrefreshed on waking. The prevalence of insomnia increases with age. Other risk factors include psychological factors, stress, daytime napping, and hyperarousal.

METHODS AND OUTCOMES

We conducted a systematic review and aimed to answer the following clinical question: What are the effects of non-drug treatments for primary insomnia in older people (aged 60 years and older)? We searched: Medline, Embase, The Cochrane Library, and other important databases up to May 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).

RESULTS

We found 14 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

CONCLUSIONS

In this systematic review, we present information relating to the effectiveness and safety of the following interventions: cognitive behavioural therapy for insomnia (CBT-I), exercise programmes, and timed exposure to bright light.

摘要

引言

高达40%的老年人患有失眠症,存在入睡困难、早醒或醒来后感觉没有恢复精力的问题。失眠症的患病率随年龄增长而增加。其他风险因素包括心理因素、压力、白天小睡和过度觉醒。

方法与结果

我们进行了一项系统评价,旨在回答以下临床问题:非药物治疗对老年人(60岁及以上)原发性失眠有何效果?我们检索了:截至2014年5月的Medline、Embase、Cochrane图书馆及其他重要数据库(Clinical Evidence综述会定期更新;请查看我们的网站获取本综述的最新版本)。我们纳入了来自美国食品药品监督管理局(FDA)和英国药品和医疗产品监管局(MHRA)等相关组织的危害警示。

结果

我们发现14项研究符合我们的纳入标准。我们对干预措施的证据质量进行了GRADE评估。

结论

在本系统评价中,我们提供了以下干预措施的有效性和安全性相关信息:失眠认知行为疗法(CBT-I)、锻炼计划和定时暴露于强光下。

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