Kapuria Devika, Strasser Kristen, Qasem Abdulraheem
Department of Internal Medicine, University of Missouri Kansas City, Kansas City, Missouri, USA.
Department of Hematology and Oncology, University of Missouri Kansas City, Kansas City, Missouri, USA.
BMJ Case Rep. 2015 May 12;2015:bcr2015209328. doi: 10.1136/bcr-2015-209328.
Acute liver failure is a rare but life-threatening illness with an incidence of 2-8 per million population. The most common causes of acute liver failure include drug ingestion and viral hepatitis followed by ischaemic hepatocellular injury and, less commonly, malignancy. Our patient presented with acute liver failure, which was found to be secondary to hepatic infiltration by diffuse large B-cell lymphoma. He received early treatment and has been in remission for more than a year after his initial presentation. To the best of our knowledge, our patient is the second reported survivor of acute liver failure caused by malignant hepatic infiltration by diffuse large B-cell lymphoma.
急性肝衰竭是一种罕见但危及生命的疾病，发病率为每百万人口2 - 8例。急性肝衰竭最常见的病因包括药物摄入和病毒性肝炎，其次是缺血性肝细胞损伤，较少见的是恶性肿瘤。我们的患者表现为急性肝衰竭，经发现是由弥漫性大B细胞淋巴瘤肝浸润继发所致。他接受了早期治疗，自首次发病后已缓解超过一年。据我们所知，我们的患者是第二例报道的由弥漫性大B细胞淋巴瘤恶性肝浸润导致急性肝衰竭的幸存者。
