[Results of antineoplastic chemotherapy based on the oncobiogram].

An organ culture assay for in vitro chemosensitivity testing was used to predict clinical responses of various tumors to antineoplastic chemotherapy. 9 patients with advanced mammary carcinomas, 7 patients with metastatic malignant melanomas, 1 patient with advanced ovarian cancer, 1 with bronchogenic carcinoma, 1 with metastatic leiomyosarcoma and 1 patient with a metastatic carcinoma of the sweat gland were included in the study. 20 in vitro-in vivo correlations were evaluable. 5/9 of the mammary carcinomas showed an objective response, 0/7 malignant melanomas were sensitive in vivo. Further investigations have to assess the value of chemosensitivity assays to predict clinical response for patients with solid tumors.