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Molecular cloning of the Rauscher murine leukemia virus. Disease spectrum and integration pattern.

作者信息

van der Feltz M J, Kranendonk-Odijk M E, Rhijnsburger E H, Stark J, Stoker K, de Both N J

机构信息

Department of Pathology, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands.

出版信息

Arch Virol. 1989;108(1-2):115-20. doi: 10.1007/BF01313748.

Abstract

After transfection of NIH 3T3 cells with DNA from molecularly cloned Rauscher MuLV, virus was isolated which showed a disease spectrum comparable to that of R-MuLV cloned biologically by endpoint dilution. In both cases sites of proviral integration vary from 2-5 per leukemic tissue and occur apparently at random.

摘要

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