Lee R Jay, LaPorte Dawn M, Brooks Jaysson T, Schubert Cornelius D, Deune E Gene
Orthopedics. 2015 May;38(5):e367-73. doi: 10.3928/01477447-20150504-52.
After axillary lymph node dissection (ALND), patients are cautioned against ipsilateral interventional procedures to avoid the theoretical increased risk of postoperative complications, particularly lymphedema. The authors' goal was to evaluate the complications of elective hand surgery after ALND. The authors reviewed patients presenting to their hand clinic from 1998 to 2011, selecting those with a diagnosis of breast cancer or melanoma and a history of previous ALND; the authors excluded those treated nonoperatively and those treated with elective surgery in the contralateral hand. Average age of the 22 patients meeting the criteria (20 with a history of breast cancer, 6 with preexisting lymphedema) was 53.9 years (range, 26.7 to 73.6 years) at the time of ALND and 63.1 years (range, 31.7 to 83.5 years) at the time of hand surgery. Average interval between surgeries was 9.2 years (range, 8 days to 37.3 years). Follow-up averaged 9.2 months (range, 8 days to 41.7 months). Fifteen patients were surveyed for long-term postoperative results (average surgery-to-survey interval, 4.3 years [range, 1 to 11.9 years]). Fifteen patients had uneventful postoperative recoveries, 4 had peri-incisional erythema requiring oral antibiotics, 1 had incisional pain and scarring, 1 had chronic wound-healing issues, and 1 had a dehiscence requiring a return to the operating room. In the 15 patients who completed the follow-up survey, there was no disease exacerbation in the 3 patients with preexisting lymphedema, and there were no new cases of lymphedema. Routine minor hand surgery did not result in lymphedema and did not increase existing lymphedema in these patients with previous ipsilateral ALND, but almost one-third of them had short-term complications in the postoperative recovery period.
在进行腋窝淋巴结清扫术(ALND)后,通常会告诫患者避免同侧的介入性操作,以避免理论上术后并发症风险的增加,尤其是淋巴水肿。作者的目标是评估ALND术后择期手部手术的并发症。作者回顾了1998年至2011年期间到他们手部诊所就诊的患者,选择那些诊断为乳腺癌或黑色素瘤且有既往ALND病史的患者;排除那些非手术治疗的患者以及对侧手部接受择期手术的患者。符合标准的22例患者(20例有乳腺癌病史,6例已有淋巴水肿)在进行ALND时的平均年龄为53.9岁(范围为26.7至73.6岁),在进行手部手术时的平均年龄为63.1岁(范围为31.7至83.5岁)。两次手术之间的平均间隔时间为9.2年(范围为8天至37.3年)。随访平均时间为9.2个月(范围为8天至41.7个月)。对15例患者进行了长期术后结果调查(手术至调查的平均间隔时间为4.3年[范围为1至11.9年])。15例患者术后恢复顺利,4例出现切口周围红斑,需要口服抗生素治疗,1例有切口疼痛和瘢痕形成,1例有慢性伤口愈合问题,1例切口裂开,需要返回手术室。在完成随访调查的15例患者中,3例已有淋巴水肿的患者病情未加重,且没有新的淋巴水肿病例。对于这些既往有同侧ALND的患者,常规的小型手部手术未导致淋巴水肿,也未加重现有的淋巴水肿,但其中近三分之一的患者在术后恢复期出现了短期并发症。