Molodoi Andreea Dana, Dimitriu Andreea, Andronic Cătălina Diana, Stoleriu Gabriela, Bădescu Aida, Boda D, Brănisteanu Daciana Elena
Rev Med Chir Soc Med Nat Iasi. 2015 Jan-Mar;119(1):107-11.
Pyoderma vegetans is a rare disorder that more commonly affects middle-aged persons, with a male predilection. It is characterized by vegetating lesions that coalescence into a plaque with eroded surface, covered by purulent discharge and crusts. The etiology of this disease is not known with certainty, but it is often associated with bacterial infections in immunocompromised patients. We report the case of a 73-year-old men who presented to the Iasi Dermatology Clinic with a large, irregular, relatively well-defined dermohypodermic ulcer, with infiltrated sclerosing borders, accompanied by pain, with the floor covered in the Northern part by a proliferative, vegetative bleeding area, and the rest by a yellowish secretion and cellular debris, located on the left leg. Bacteriological examination of ulcer secretion identified Pseudomonas aeruginosa. Anatomopathological examination confirmed the development of Pyoderma vegetans on chronic leg ulcer. Under specific treatment for chronic leg ulcer and eradication of infectious focus the outcome was favorable both in terms of trophic ulcer scar- ring and Pyoderma vegetans healing.
增殖性脓皮病是一种罕见的疾病，更常见于中年人群，男性更易患病。其特征为增殖性损害融合成具有糜烂表面的斑块，表面覆盖有脓性分泌物和痂皮。该病的确切病因尚不清楚，但常与免疫功能低下患者的细菌感染有关。我们报告一例73岁男性患者，其因左下肢出现一个大的、不规则的、边界相对清晰的真皮皮下溃疡，边界有浸润性硬化，伴有疼痛，溃疡底部北部为增生性、增殖性出血区，其余部分为淡黄色分泌物和细胞碎屑，而就诊于雅西皮肤科诊所。溃疡分泌物的细菌学检查发现铜绿假单胞菌。组织病理学检查证实慢性腿部溃疡上发生了增殖性脓皮病。在针对慢性腿部溃疡的特定治疗以及根除感染灶后，无论是营养性溃疡瘢痕形成还是增殖性脓皮病愈合方面，结果均良好。
