Stevenson B R, Anderson J M, Braun I D, Mooseker M S
Department of Biology, Yale University, New Haven, CT 06511.
Biochem J. 1989 Oct 15;263(2):597-9. doi: 10.1042/bj2630597.
A comparison was made of the phosphate content of the tight-junction-specific protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance, a parameter reflective of tight-junctional permeability. Analysis revealed that the ZO-1 from the low-resistance strain contained approximately twice as much phosphate as that from the high-resistance strain.
对两株上皮细胞电阻不同(反映紧密连接通透性的一个参数)的马-达二氏犬肾细胞中紧密连接特异性蛋白ZO-1的磷酸盐含量进行了比较。分析显示,低电阻菌株的ZO-1所含磷酸盐约为高电阻菌株的两倍。