促肾上腺皮质激素释放因子结合蛋白是一种糖蛋白。
Corticotropin-releasing factor-binding protein is a glycoprotein.
作者信息
Suda T, Sumitomo T, Tozawa F, Ushiyama T, Demura H
机构信息
Department of Medicine, Tokyo Women's Medical College, Japan.
出版信息
Biochem Biophys Res Commun. 1989 Dec 15;165(2):703-7. doi: 10.1016/s0006-291x(89)80023-3.
Human corticotropin-releasing factor-binding protein (hCRF-BP), a 38,000 dalton protein, specifically binds hCRF in plasma. CRF-BP-CRF complex adsorbed to concanavalin-A-Sepharose and its Mr decreased after treatment with endoglycosidase H or glycopeptidase A. The binding of CRF-BP to CRF decreased after treatment with endoglycosidase H. These results indicate that the CRF-BP is a glycoprotein that contains asparagine N-linked-type oligosaccharides, and such oligosaccharide chains are important for CRF-BP binding.
人促肾上腺皮质激素释放因子结合蛋白（hCRF - BP）是一种38000道尔顿的蛋白质，可特异性结合血浆中的hCRF。吸附在伴刀豆球蛋白A - 琼脂糖上的CRF - BP - CRF复合物，经内切糖苷酶H或糖肽酶A处理后其分子量降低。用内切糖苷酶H处理后，CRF - BP与CRF的结合减少。这些结果表明，CRF - BP是一种含有天冬酰胺N - 连接型寡糖的糖蛋白，且这种寡糖链对于CRF - BP的结合很重要。
Zotero 插件