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单纯性肾囊肿与腹主动脉瘤的关联及其对血管腔内动脉瘤修复术后肾功能的影响。

The association of simple renal cysts with abdominal aortic aneurysms and their impact on renal function after endovascular aneurysm repair.

作者信息

Spanos Konstantinos, Rountas Christos, Saleptsis Vasileios, Athanasoulas Athanasios, Fezoulidis Ioannis, Giannoukas Athanasios D

机构信息

Department of Vascular Surgery, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece

Department of Radiology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

出版信息

Vascular. 2016 Apr;24(2):150-6. doi: 10.1177/1708538115586917. Epub 2015 May 12.

DOI:10.1177/1708538115586917
PMID:25972033
Abstract

We validated the association of simple renal cysts with abdominal aortic aneurysm and other cardiovascular factors and assessed simple renal cysts' impact on renal function before and after endovascular abdominal aortic aneurysm repair. A retrospective analysis of prospectively collected data was conducted. Computed tomography angiograms of 100 consecutive male patients with abdominal aortic aneurysm who underwent endovascular abdominal aortic aneurysm repair (Group 1) were reviewed and compared with 100 computed tomography angiogram of aged-matched male patients without abdominal aortic aneurysm (Group 2). Patients' demographic data, risk factors, abdominal aortic aneurysm diameter, the presence of simple renal cyst and laboratory tests were recorded. No difference was observed between the two groups in respect to other cardiovascular risk factors except hyperlipidemia with higher prevalence in Group 1 (p < 0.05). Presence of simple renal cysts was independently associated with age (p < 0.05) and abdominal aortic aneurysm (p = 0.0157). There was no correlation between simple renal cysts and abdominal aortic aneurysm size or pre-operative creatinine and urea levels. No difference was observed in post-operative creatinine and urea levels either immediately after endovascular abdominal aortic aneurysm repair or in 12-month follow-up. In male patients, the presence of simple renal cysts is associated with abdominal aortic aneurysm and is increasing with age. However, their presence is neither associated with impaired renal function pre-endovascular abdominal aortic aneurysm repair and post-endovascular abdominal aortic aneurysm repair nor after 12-month follow-up.

摘要

我们验证了单纯性肾囊肿与腹主动脉瘤及其他心血管因素之间的关联,并评估了单纯性肾囊肿在血管腔内腹主动脉瘤修复术前和术后对肾功能的影响。我们对前瞻性收集的数据进行了回顾性分析。回顾了连续100例接受血管腔内腹主动脉瘤修复术的男性腹主动脉瘤患者(第1组)的计算机断层血管造影,并与100例年龄匹配的无腹主动脉瘤男性患者的计算机断层血管造影(第2组)进行比较。记录患者的人口统计学数据、危险因素、腹主动脉瘤直径、单纯性肾囊肿的存在情况及实验室检查结果。除高脂血症在第1组中的患病率较高外(p<0.05),两组在其他心血管危险因素方面未观察到差异。单纯性肾囊肿的存在与年龄(p<0.05)和腹主动脉瘤(p=0.0157)独立相关。单纯性肾囊肿与腹主动脉瘤大小或术前肌酐和尿素水平之间无相关性。在血管腔内腹主动脉瘤修复术后即刻或12个月随访中,术后肌酐和尿素水平均未观察到差异。在男性患者中,单纯性肾囊肿的存在与腹主动脉瘤相关,且随年龄增加而增加。然而,它们的存在与血管腔内腹主动脉瘤修复术前、术后及12个月随访后的肾功能损害均无关。

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