Smistad G, Waaler T, Roksvaag P O
Acta Pharm Nord. 1989;1(1):1-8.
A gas-liquid chromatographic method for the determination of epoxidized vegetable oils (EVO), such as epoxidized soybean oil and epoxidized linseed oil, in aqueous solutions is described. The EVOs are extracted with n-hexane and transesterified to the methyl esters by sodium methoxide in methanol. 3% OV-210 is used as the stationary phase. The weakest standard solution corresponds to 5 micrograms/l (5 ppb) of EVO in an aqueous sample. The reproducibility of a single analysis is 5%. The method is used for the determination of EVO in intravenous fluids stored in flexible polyvinyl chloride bags.
本文描述了一种气相色谱法，用于测定水溶液中的环氧化植物油（EVO），如环氧大豆油和环氧亚麻籽油。EVO用正己烷萃取，并用甲醇中的甲醇钠进行酯交换反应生成甲酯。使用3%的OV-210作为固定相。最弱的标准溶液相当于水样中5微克/升（5 ppb）的EVO。单次分析的重现性为5%。该方法用于测定储存在软质聚氯乙烯袋中的静脉输液中的EVO。
