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准直器影响参数对单光子发射计算机断层扫描(SPECT)图像质量的研究:一项蒙特卡洛研究

Investigation of Collimator Influential Parameter on SPECT Image Quality: a Monte Carlo Study.

作者信息

Banari Bahnamiri Sh

机构信息

Assistant Professor of Nuclear Physics, Tabari University of Babol, Iran;

出版信息

J Biomed Phys Eng. 2015 Mar 4;5(1):39-48. eCollection 2015 Mar.

Abstract

BACKGROUND

Obtaining high quality images in Single Photon Emission Tomography (SPECT) device  is the most important goal in nuclear medicine. Because if image quality is low, the possibility of making a mistake in diagnosing and treating the patient will rise. Studying effective factors in spatial resolution of imaging systems is thus deemed to be vital. One of the most important factors in SPECT imaging in nuclear medicine is the use of an appropriate collimator for a certain radiopharmaceutical feature in order to create the best image as it can be effective in the quantity of Full Width at Half Maximum (FWHM) which is the main parameter  in spatial resolution.

METHOD

In this research, the simulation of the detector and collimator of SPECT imaging device, Model HD3 made by Philips Co. and the investigation of important factors on the collimator were carried out using MCNP-4c code.

RESULTS

The results of the experimental measurments and simulation calculations revealed a relative difference of less than 5% leading to the confirmation of the accuracy of conducted simulation MCNP code calculation.

CONCLUSION

This is the first essential step in the design and modelling of new collimators used for creating high quality images in nuclear medicine.

摘要

背景

在单光子发射断层扫描(SPECT)设备中获取高质量图像是核医学的最重要目标。因为如果图像质量低,在诊断和治疗患者时出错的可能性就会增加。因此,研究成像系统空间分辨率的有效因素被认为至关重要。核医学SPECT成像中最重要的因素之一是针对特定放射性药物特性使用合适的准直器,以便创建最佳图像,因为它可以影响半高宽(FWHM)的量,而半高宽是空间分辨率的主要参数。

方法

在本研究中,使用MCNP - 4c代码对飞利浦公司生产的HD3型SPECT成像设备的探测器和准直器进行了模拟,并对准直器的重要因素进行了研究。

结果

实验测量和模拟计算结果显示相对差异小于5%,从而证实了所进行的模拟MCNP代码计算的准确性。

结论

这是设计和建模用于在核医学中创建高质量图像的新型准直器的第一个重要步骤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2112/4417619/5ee5502cefd4/jbpe-5-39-g001.jpg

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