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错误的推理会驱逐正确的吗?

Does bad inference drive out good?

作者信息

Marozzi Marco

机构信息

University of Calabria, Rende, Italy.

出版信息

Clin Exp Pharmacol Physiol. 2015 Jul;42(7):727-33. doi: 10.1111/1440-1681.12422.

Abstract

The (mis)use of statistics in practice is widely debated, and a field where the debate is particularly active is medicine. Many scholars emphasize that a large proportion of published medical research contains statistical errors. It has been noted that top class journals like Nature Medicine and The New England Journal of Medicine publish a considerable proportion of papers that contain statistical errors and poorly document the application of statistical methods. This paper joins the debate on the (mis)use of statistics in the medical literature. Even though the validation process of a statistical result may be quite elusive, a careful assessment of underlying assumptions is central in medicine as well as in other fields where a statistical method is applied. Unfortunately, a careful assessment of underlying assumptions is missing in many papers, including those published in top class journals. In this paper, it is shown that nonparametric methods are good alternatives to parametric methods when the assumptions for the latter ones are not satisfied. A key point to solve the problem of the misuse of statistics in the medical literature is that all journals have their own statisticians to review the statistical method/analysis section in each submitted paper.

摘要

统计学在实际中的(误)用引发了广泛讨论,医学领域就是一个讨论尤为活跃的领域。许多学者强调,大量已发表的医学研究存在统计错误。有人指出,像《自然医学》和《新英格兰医学杂志》这样的顶级期刊发表的相当一部分论文存在统计错误,且对统计方法的应用记录不佳。本文加入了关于医学文献中统计学(误)用的讨论。尽管统计结果的验证过程可能相当难以捉摸,但对基础假设进行仔细评估在医学以及其他应用统计方法的领域中都至关重要。不幸的是,许多论文,包括顶级期刊发表的论文,都缺少对基础假设的仔细评估。本文表明,当参数方法的假设不满足时,非参数方法是参数方法的良好替代方案。解决医学文献中统计误用问题的一个关键要点是,所有期刊都应有自己的统计学家来审阅每篇投稿论文的统计方法/分析部分。

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