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用于临床应用的腹部检查定量指标的开发:一项初步研究。

Development of the quantitative indicator of abdominal examination for clinical application: a pilot study.

作者信息

Ko Seok-Jae, Lee Hyunju, Kim Seul-Ki, Kim Minji, Kim Jinsung, Lee Beom-Joon, Park Jae-Woo

机构信息

Department of Internal Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

出版信息

J Altern Complement Med. 2015 Jun;21(6):358-63. doi: 10.1089/acm.2014.0185. Epub 2015 May 14.

DOI:10.1089/acm.2014.0185
PMID:25974704
Abstract

OBJECTIVES

Abdominal examination (AE) is the evaluation of the status of illness by examining the abdominal region in traditional Korean medicine (TKM). Although AE is currently considered an important diagnostic method in TKM, owing to its clinical usage, no studies have been conducted to objectively assess its accuracy and develop standards.

DESIGN

Twelve healthy subjects and 21 patients with functional dyspepsia have participated in this study. The patients were classified into epigastric discomfort group (n=11) and epigastric discomfort with tenderness group (n=10) according to the clinical diagnosis by AE. After evaluating the subjective epigastric discomfort in all subjects, two independent clinicians measured the pressure pain threshold (PPT) two times at an acupoint (CV 14) using an algometer. We then assessed the interrater and intrarater reliability of the PPT measurements and evaluated the validity (sensitivity and specificity) via a receiver operating characteristic plot and optimal cutoff value.

RESULTS

The results of the interrater reliability test showed a very strong correlation (correlation coefficient range: 0.82-0.91). The results of intrarater reliability test also showed a higher than average correlation (intraclass correlation coefficient: 0.58-0.70). The optimal cutoff value of PPT in the epigastric area was 1.8 kg/cm(2) with 100% sensitivity and 54.54% specificity.

CONCLUSIONS

PPT measurements in the epigastric area with an algometer demonstrated high reliability and validity for AE, which makes this approach potentially useful in clinical applications as a new quantitative measurement in TKM.

摘要

目的

腹部检查(AE)是传统韩医学(TKM)中通过检查腹部区域来评估病情的方法。尽管目前AE在TKM中被认为是一种重要的诊断方法,但由于其临床应用情况,尚未有研究对其准确性进行客观评估并制定标准。

设计

12名健康受试者和21名功能性消化不良患者参与了本研究。根据AE的临床诊断,将患者分为上腹部不适组(n = 11)和上腹部不适伴压痛组(n = 10)。在评估所有受试者的主观上腹部不适后,两名独立的临床医生使用压力痛觉计在穴位(CV 14)处测量两次压力痛阈(PPT)。然后,我们评估了PPT测量的评分者间和评分者内信度,并通过受试者工作特征曲线和最佳截断值评估了效度(敏感性和特异性)。

结果

评分者间信度测试结果显示出非常强的相关性(相关系数范围:0.82 - 0.91)。评分者内信度测试结果也显示出高于平均水平的相关性(组内相关系数:0.58 - 0.70)。上腹部区域PPT的最佳截断值为1.8 kg/cm²,敏感性为100%,特异性为54.54%。

结论

使用压力痛觉计测量上腹部区域的PPT对AE具有较高的信度和效度,这使得这种方法作为TKM中的一种新的定量测量方法在临床应用中具有潜在的实用性。

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