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[健康保险数据库对于研究哮喘患病率空间差异的相关性:法国东南部的一项研究]

[Relevance of the health insurance databases to study spatial disparities in asthma prevalence: A study in southeastern France].

作者信息

Bocquier A, El-Haïk Y, Jardin M, Cortaredona S, Nauleau S, Verger P

机构信息

Observatoire régional de la santé Provence-Alpes-Côte d'Azur (ORS PACA), 23, rue Stanislas-Torrents, 13006 Marseille, France; Inserm, UMR912 (SESSTIM), 13006 Marseille, France; UMR_S912, IRD, Aix-Marseille université, 13006 Marseille, France.

Observatoire régional de la santé Provence-Alpes-Côte d'Azur (ORS PACA), 23, rue Stanislas-Torrents, 13006 Marseille, France; Service pharmacie, CHU Timone, AP-HM, 13385 Marseille, France.

出版信息

Rev Epidemiol Sante Publique. 2015 Jun;63(3):155-62. doi: 10.1016/j.respe.2015.03.122. Epub 2015 May 12.

Abstract

BACKGROUND

Data on asthma prevalence at a small-area level would be useful to set up and monitor French local public health policies. This study, based on drug reimbursement databases in southeastern France, aimed to (1) compare asthma-like disorders prevalence estimated by using three different indicators; (2) study sociodemographic characteristics associated with these indicators; (3) verify whether these indicators are equivalent to study geographical disparities of the asthma-like disorders prevalence at a small-area level.

METHODS

The study was conducted among the beneficiaries of the National Health Insurance Fund aged 18-44 years residing in southeastern France in 2010 (n=1,371,816). Using data on asthma drugs reimbursements (therapeutic class R03), we built three indicators to assess asthma-like disorders prevalence: at least 1, 2 or 3 purchase(s) in 2010. We analyzed sociodemographic characteristics associated with these indicators, and their geographical disparities at a small-area level using multilevel logistic regression models.

RESULTS

The crude asthma-like disorders prevalence varied between 2.6 % and 8.4 % depending on the indicator. It increased with age, was higher for women than for men, and among low-income people for all three indicators. We measured significant geographical disparities. Areas with high prevalence rates were the same regardless of the indicator.

CONCLUSION

The indicators built in this study can be useful to identify high prevalence areas. They could contribute to launch discussion on environmental health issues at the local level.

摘要

背景

小区域层面的哮喘患病率数据对于制定和监测法国地方公共卫生政策很有用。本研究基于法国东南部的药品报销数据库,旨在:(1)比较使用三种不同指标估算的哮喘样疾病患病率;(2)研究与这些指标相关的社会人口学特征;(3)验证这些指标是否等同于在小区域层面研究哮喘样疾病患病率的地理差异。

方法

该研究在2010年居住于法国东南部的18 - 44岁国家健康保险基金受益人中进行(n = 1,371,816)。利用哮喘药物报销数据(治疗类别R03),我们构建了三个指标来评估哮喘样疾病患病率:2010年至少有1次、2次或3次购买记录。我们分析了与这些指标相关的社会人口学特征,以及使用多水平逻辑回归模型在小区域层面的地理差异。

结果

根据指标不同,哮喘样疾病的粗患病率在2.6%至8.4%之间变化。患病率随年龄增加而上升,女性高于男性,且在所有三个指标中低收入人群的患病率更高。我们测量到了显著的地理差异。无论使用哪个指标,患病率高的区域都是相同的。

结论

本研究构建的指标有助于识别高患病率地区。它们可有助于在地方层面引发关于环境卫生问题的讨论。

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