Amaratunga N A
Division of Oral Surgery, Faculty of Dental Sciences, University of Peradeniya, Sri Lanka.
Br J Oral Maxillofac Surg. 1989 Dec;27(6):451-8. doi: 10.1016/s0266-4356(89)80002-6.
Thirty seven infants with Pierre Robin syndrome were compared with children who had isolated cleft palate. A female preponderance was seen in both groups. Skeletal II jaw relation was observed in 32% of the children with isolated cleft palate. Associated malformations such as hypertelorism and strabismus were more common in infants with Pierre Robin syndrome and also in those with isolated cleft palate combined with a skeletal II jaw relationship when compared with infants who had cleft palate with a skeletal I jaw relationship. The frequency of hypodontia also was greater in the former two groups than in the latter. Furthermore, no difference was found in the frequencies of U- and V-shaped clefts. The frequencies of near relatives with clefts were also not different between groups. Whilst it may be possible to observe from these findings an association between Pierre Robin syndrome and isolated cleft palate, it is difficult to conclude that they support any of the postulates regarding the aetiology of Pierre Robin syndrome.
将37例Pierre Robin综合征患儿与单纯腭裂患儿进行了比较。两组均以女性居多。在单纯腭裂患儿中，32%观察到骨骼II类颌关系。与具有骨骼I类颌关系的腭裂婴儿相比，诸如眼距过宽和斜视等相关畸形在Pierre Robin综合征婴儿以及具有骨骼II类颌关系的单纯腭裂婴儿中更为常见。前两组的牙缺失发生率也高于后一组。此外，U型和V型腭裂的发生率没有差异。两组之间有腭裂近亲的频率也没有差异。虽然从这些发现中可能可以观察到Pierre Robin综合征与单纯腭裂之间的关联，但很难得出它们支持任何关于Pierre Robin综合征病因假说的结论。
