Shah Bijal M, Mezzio Dylan J, Ho Jackie, Ip Eric J
Department of Social, Behavioral & Administrative Sciences, College of Pharmacy, Touro University California, Vallejo, CA, USA.
College of Pharmacy, Touro University California, Vallejo, CA, USA.
J Diabetes Complications. 2015 Aug;29(6):794-800. doi: 10.1016/j.jdiacomp.2015.04.009. Epub 2015 Apr 24.
To determine the relationship between ABC goal attainment, depression, and health-related quality of life (HRQoL) among a national sample of patients with type 2 diabetes (T2DM).
A retrospective, cross-sectional analysis was performed examining 808 non-pregnant patients ≥20 years old with T2DM from the National Health and Nutrition Examination Survey (NHANES) 2007-2012. ABC goals were defined as HbA1c<7%, BP<130/80 mm Hg, and LDL-C<100 mg/dL. Patient characteristics associated with ABC goal attainment were examined.
Overall, 23.7% of participants achieved simultaneous ABC goals. Severe depression was significantly associated with lower rates of ABC goal attainment compared to those with no depression (5.0% vs. 25.4%, p=0.048). ABC goal attainment rates were lower among females, Hispanic and non-Hispanic black minority groups, and patients with a duration of diabetes over five years, while increased visits with health care professionals were significantly associated with meeting all three ABC goals for patients with T2DM.
The relationship between simultaneous ABC goal attainment, depression and HRQoL is complex. Patients with T2DM unable to meet ABC goals may benefit from increased contact with health care professionals.
在全国范围内的2型糖尿病(T2DM)患者样本中,确定ABC目标达成情况、抑郁与健康相关生活质量(HRQoL)之间的关系。
进行了一项回顾性横断面分析,研究对象为2007 - 2012年美国国家健康与营养检查调查(NHANES)中808名年龄≥20岁的非妊娠T2DM患者。ABC目标定义为糖化血红蛋白(HbA1c)<7%、血压(BP)<130/80 mmHg以及低密度脂蛋白胆固醇(LDL-C)<100 mg/dL。研究了与ABC目标达成相关的患者特征。
总体而言,23.7%的参与者同时实现了ABC目标。与无抑郁的患者相比,严重抑郁与ABC目标达成率较低显著相关(5.0%对25.4%,p = 0.048)。女性、西班牙裔和非西班牙裔黑人少数群体以及糖尿病病程超过五年的患者中,ABC目标达成率较低,而增加与医护人员的就诊次数与T2DM患者实现所有三个ABC目标显著相关。
同时实现ABC目标、抑郁和HRQoL之间的关系很复杂。无法实现ABC目标的T2DM患者可能会从增加与医护人员的接触中受益。