Moore Dwayne R J, Breton Roger L, DeLong Tod R, Ferson Scott, Lortie John P, MacDonald Drew B, McGrath Richard, Pawlisz Andrzej, Svirsky Susan C, Teed R Scott, Thompson Ryan P, Whitfield Aslund Melissa
Intrinsik Environmental Sciences, New Gloucester, Maine, USA.
Intrinsik Environmental Sciences, Ottawa, Ontario, Canada.
Integr Environ Assess Manag. 2016 Jan;12(1):174-84. doi: 10.1002/ieam.1661. Epub 2015 Jul 30.
A probabilistic risk assessment was conducted to characterize risks to a representative piscivorous mammal (mink, Mustela vison) and a representative carnivorous mammal (short-tailed shrew, Blarina brevicauda) exposed to PCBs, dioxins, and furans in the Housatonic River area downstream of the General Electric (GE) facility in Pittsfield, Massachusetts. Contaminant exposure was estimated using a probabilistic total daily intake model and parameterized using life history information of each species and concentrations of PCBs, dioxins, and furans in prey collected in the Housatonic River study area. The effects assessment preferentially relied on dose-response curves but defaulted to benchmarks or other estimates of effect when there were insufficient toxicity data. The risk characterization used a weight of evidence approach. Up to 3 lines of evidence were used to estimate risks to the selected mammal species: 1) probabilistic exposure and effects modeling, 2) field surveys, and 3) species-specific feeding or field studies. The weight of evidence assessment indicated a high risk for mink and an intermediate risk for short-tailed shrew.
进行了概率风险评估,以描述在马萨诸塞州皮茨菲尔德通用电气(GE)设施下游的胡萨托尼克河地区,接触多氯联苯、二恶英和呋喃的代表性食鱼哺乳动物(水貂,鼬属水貂)和代表性食肉哺乳动物(短尾鼩鼱,短尾鼩鼱属)所面临的风险。使用概率总日摄入量模型估计污染物暴露,并根据每个物种的生活史信息以及在胡萨托尼克河研究区域收集的猎物中多氯联苯、二恶英和呋喃的浓度进行参数化。效应评估优先依赖剂量反应曲线,但在毒性数据不足时采用基准或其他效应估计值。风险特征描述采用证据权重法。使用多达3条证据线来估计选定哺乳动物物种面临的风险:1)概率暴露和效应建模,2)实地调查,3)特定物种的觅食或实地研究。证据权重评估表明水貂面临高风险,短尾鼩鼱面临中等风险。