Koot A W A, Visscher A P, Huits R M H G
Acta Clin Belg. 2015 Aug;70(4):301-3. doi: 10.1179/2295333715Y.0000000005. Epub 2015 May 15.
Splenomegaly is a common finding in chronic hepatitis B infection. We present the case of a man with an acute flare of chronic hepatitis B infection, where splenomegaly in absence of portal hypertension led to the diagnosis of splenic marginal zone lymphoma (SMZL) with bone marrow involvement. Adequate suppression of the hepatitis B virus (HBV) viral load with tenofovir resulted in complete remission of the lymphoma.
脾肿大是慢性乙型肝炎感染中的常见表现。我们报告一例慢性乙型肝炎感染急性发作的男性病例,该患者在无门静脉高压的情况下出现脾肿大,最终诊断为伴有骨髓受累的脾边缘区淋巴瘤(SMZL)。使用替诺福韦充分抑制乙型肝炎病毒(HBV)病毒载量后,淋巴瘤完全缓解。