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Toward Resolving the Paradox of the Critical Role of the DosR Regulon in Mycobacterium tuberculosis Persistence and Active Disease.

作者信息

Voskuil Martin I, Schlesinger Larry S

机构信息

1 University of Colorado Denver School of Medicine Aurora, Colorado.

出版信息

Am J Respir Crit Care Med. 2015 May 15;191(10):1103-5. doi: 10.1164/rccm.201503-0424ED.

DOI:10.1164/rccm.201503-0424ED
PMID:25978571
Abstract
摘要

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Toward Resolving the Paradox of the Critical Role of the DosR Regulon in Mycobacterium tuberculosis Persistence and Active Disease.关于解决DosR调控子在结核分枝杆菌潜伏和活动性疾病中的关键作用这一矛盾问题
Am J Respir Crit Care Med. 2015 May 15;191(10):1103-5. doi: 10.1164/rccm.201503-0424ED.
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Cross-reactive immunity to Mycobacterium tuberculosis DosR regulon-encoded antigens in individuals infected with environmental, nontuberculous mycobacteria.感染环境非结核分枝杆菌的个体对结核分枝杆菌DosR调控子编码抗原的交叉反应性免疫。
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Strains of the East Asian (W/Beijing) lineage of Mycobacterium tuberculosis are DosS/DosT-DosR two-component regulatory system natural mutants.东亚(W/北京)分枝杆菌株是 DosS/DosT-DosR 双组分调控系统天然突变体。
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