Pancari Philip, Mehra Ranee
Department of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
Department of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
Surg Oncol Clin N Am. 2015 Jul;24(3):437-54. doi: 10.1016/j.soc.2015.03.004.
The use of systemic therapy as part of curative treatment and palliation is an evolving paradigm for squamous cell cancer of the head and neck (SCCHN), which historically has been treated with local modalities. At present, the treatment armamentarium includes traditional cytotoxic therapy, targeted biological agents, and emerging immunotherapeutics. This article discusses the use of all of these systemic approaches for the curative and palliative treatment of SCCHN.
全身治疗作为根治性治疗和姑息治疗的一部分,是头颈部鳞状细胞癌(SCCHN)不断发展的治疗模式,而头颈部鳞状细胞癌在历史上一直采用局部治疗方法。目前,治疗手段包括传统的细胞毒性疗法、靶向生物制剂和新兴的免疫疗法。本文讨论了所有这些全身治疗方法在头颈部鳞状细胞癌根治性和姑息性治疗中的应用。