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免疫功能正常男性的D组沙门氏菌尿路感染

Group d salmonella urinary tract infection in an immunocompetent male.

作者信息

Jehangir Asad, Poudel Dilli, Fareedy Shoaib Bilal, Salman Ahmed, Qureshi Anam, Jehangir Qasim, Alweis Richard

机构信息

Department of Internal Medicine, Reading Health System, Spruce Street/6th Avenue, West Reading, PA 19610, USA.

King Edward Medical University, Mayo Hospital Road, Nelagumbad, Anarkali, Lahore 54000, Pakistan.

出版信息

Case Rep Infect Dis. 2015;2015:608632. doi: 10.1155/2015/608632. Epub 2015 Apr 23.

Abstract

A 62-year-old male with past medical history of benign prostatic hyperplasia presented to the emergency department with complaints of decreased urinary flow, inability to fully empty his bladder, and gross hematuria. Physical examination was unremarkable. Urinalysis revealed large amount of blood and more than 700 white blood cells suggesting a urinary tract infection. Urine culture grew group D Salmonella greater than 100,000 colony-forming units per mL. He was prescribed 6 weeks of trimethoprim/sulfamethoxazole and had resolution of symptoms. Retrospectively, he reported a 3-day history of watery diarrhea about a week prior to onset of urinary symptoms that was presumed to be the hematogenous source in this case. Urinary tract infection from nontyphoidal Salmonella (NTS) is rare and is usually associated with immunosuppression, chronic diseases, such as diabetes or structural abnormalities of the genitourinary tract. Genitourinary tract abnormalities previously reported in the literature that predispose to nontyphoidal Salmonella urinary tract infection include nephrolithiasis, chronic pyelonephritis, retrovesicular fistula, urethrorectal fistula, hydrocele, and post-TURP. We present an exceedingly uncommon case of 62-year-old male with group D Salmonella urinary tract infection predisposed by his history of benign prostatic hyperplasia.

摘要

一名62岁男性,有良性前列腺增生病史,因排尿困难、膀胱排空不全及肉眼血尿就诊于急诊科。体格检查无异常。尿液分析显示大量血液及700多个白细胞,提示泌尿系统感染。尿培养结果显示D组沙门氏菌每毫升菌落形成单位超过100,000个。给他开了6周的甲氧苄啶/磺胺甲恶唑,症状得以缓解。回顾性分析,他报告在出现泌尿系统症状前约一周有3天的水样腹泻病史,推测这是该病例的血行感染源。非伤寒沙门氏菌(NTS)引起的泌尿系统感染很少见,通常与免疫抑制、慢性疾病(如糖尿病)或泌尿生殖道结构异常有关。文献中先前报道的易引发非伤寒沙门氏菌泌尿系统感染的泌尿生殖道异常包括肾结石、慢性肾盂肾炎、膀胱后瘘、尿道直肠瘘、鞘膜积液及经尿道前列腺电切术后。我们报告了一例极为罕见的62岁男性因良性前列腺增生病史而引发D组沙门氏菌泌尿系统感染的病例。

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