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孕妇使用阿片类药物与新生儿戒断综合征的增加:代价是什么?

Opioid use in pregnant women and the increase in neonatal abstinence syndrome: what is the cost?

作者信息

Roussos-Ross Kay, Reisfield Gary, Elliot Iain, Dalton Susan, Gold Mark

机构信息

From the Division of Gynecology (KRR), Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, FL; Department of Psychiatry (KRR, GR), University of Florida College of Medicine, Gainesville, FL; University of Florida College of Medicine (IE, SD), Gainesville, FL; and Department of Psychiatry and McKnight Brain Institute MG, University of Florida College of Medicine, Gainesville, FL.

出版信息

J Addict Med. 2015 May-Jun;9(3):222-5. doi: 10.1097/ADM.0000000000000122.

Abstract

OBJECTIVES

To investigate the length of stay for observation and treatment of neonatal abstinence syndrome (NAS), as well as the hospital costs associated with the medical care of affected newborns.

METHODS

A retrospective chart review was conducted at Shands Hospital at the University of Florida, Gainesville, Florida. Data were collected for newborns diagnosed with NAS, including their hospital length of stay and the associated hospital charges, from December 1, 2008, to November 30, 2011.

RESULTS

One hundred-sixty eligible newborns were included in the study. During the 3-year study period, hospital charges related to the diagnosis and treatment of NAS increased from $1.1 million per year to $1.8 million per year. Compared with the cost of caring for newborns without the risk of NAS, an additional $4.1 million was spent in the medical care of these newborns.

CONCLUSIONS

The costs associated with treating newborns with NAS are exponentially higher than the costs associated with newborns not affected with NAS. The societal costs associated with treatment of newborns with NAS, as well as infant symptomatology experienced with NAS, can be reduced by encouraging physicians to be proactive in screening for drug use, urging women who use chronic opioids to actively engage in family planning and contraception, and encouraging pregnant women who use opioids to seek substance treatment.

摘要

目的

研究新生儿戒断综合征(NAS)观察与治疗的住院时长,以及受影响新生儿医疗护理的住院费用。

方法

在佛罗里达州盖恩斯维尔市佛罗里达大学尚德医院进行回顾性病历审查。收集2008年12月1日至2011年11月30日期间诊断为NAS的新生儿的数据,包括其住院时长及相关住院费用。

结果

160名符合条件的新生儿纳入研究。在3年研究期间,与NAS诊断和治疗相关的住院费用从每年110万美元增至每年180万美元。与护理无NAS风险新生儿的费用相比,这些新生儿的医疗护理额外花费410万美元。

结论

治疗NAS新生儿的费用比治疗未受NAS影响新生儿的费用呈指数级增长。通过鼓励医生积极筛查药物使用情况、敦促使用慢性阿片类药物的女性积极参与计划生育和避孕,以及鼓励使用阿片类药物的孕妇寻求药物治疗,可降低与治疗NAS新生儿相关的社会成本以及NAS患儿出现的症状。

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