特比萘芬的体内临床前评估。

Preclinical evaluation of terbinafine in vivo.

作者信息

Mieth H, Petranyi G

出版信息

Clin Exp Dermatol. 1989 Mar;14(2):104-7. doi: 10.1111/j.1365-2230.1989.tb00902.x.

DOI:10.1111/j.1365-2230.1989.tb00902.x

Abstract

The fungicidal activity of terbinafine which has been demonstrated in vitro for several strains of dermatophyte, filamentous and dimorphic fungi, has been demonstrated in vivo in model systems for dermatophytoses. This activity is accompanied by a fast onset of action which leads to superior antifungal efficacy when compared with fungistatic drugs.

摘要

特比萘芬对多种皮肤癣菌、丝状真菌和双相真菌菌株的体外杀菌活性已在皮肤癣菌病的模型系统中得到体内验证。与抑菌药物相比，这种活性伴随着快速起效，从而产生卓越的抗真菌疗效。