de Baere T, Tselikas L, Pearson E, Yevitch S, Boige V, Malka D, Ducreux M, Goere D, Elias D, Nguyen F, Deschamps F
Gustave-Roussy Cancer Campus, Institut Gustave-Roussy, 112, rue Édouard-Vaillant, 94805 Villejuif, France.
Gustave-Roussy Cancer Campus, Institut Gustave-Roussy, 112, rue Édouard-Vaillant, 94805 Villejuif, France.
Diagn Interv Imaging. 2015 Jun;96(6):647-54. doi: 10.1016/j.diii.2015.04.004. Epub 2015 May 16.
Interventional oncology is developing rapidly as a result of advances in imaging and medical devices. Although the treatments offered are recent and not yet fully validated in the guidelines, they allow non-invasive curative treatments to be offered to a growing number of patients. When it is used in a highly selected patients with less than three metastases under 2-3cm in size, percutaneous tumor ablation offers local efficacy similar to excision surgery with considerable sparing of the parenchyma, both for lung and liver metastases. Hepatic intra-arterial therapies (chemotherapy, radioembolization, and chemoembolization) are now "salvage" methods after chemotherapy has failed and are being assessed in earlier lines of treatment.
由于成像技术和医疗设备的进步,介入肿瘤学正在迅速发展。尽管所提供的治疗方法是新出现的,尚未在指南中得到充分验证,但它们使越来越多的患者能够接受非侵入性的根治性治疗。当用于高度选择的、转移灶少于三个且大小在2 - 3厘米以下的患者时,经皮肿瘤消融术在局部疗效上与切除手术相似,对肺和肝转移灶的实质组织有相当程度的保留。肝动脉内治疗(化疗、放射性栓塞和化学栓塞)目前是化疗失败后的“挽救”方法,并且正在早期治疗阶段进行评估。