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釉质成熟过程中晶体生长的控制。

Control of crystal growth during enamel maturation.

作者信息

Robinson C, Kirkham J, Stonehouse N J, Shore R C

机构信息

Department of Oral Biology, School of Dentistry, Leeds, U.K.

出版信息

Connect Tissue Res. 1989;22(1-4):139-45.

PMID:2598665
Abstract

Attempts to promote crystal growth in maturation stage enamel from rat incisors were carried out by incubation in saturated solutions of calcium phosphate. Resulting crystallites were visualised in the TEM and the dimensions of their profiles measured. No crystal growth was observed unless the maturation stage enamel was first pretreated with either 8M urea or sodium hypochlorite to remove residual protein matrix. The results suggest that the protein matrix plays an important role in the control of crystal growth in vivo.

摘要

通过在磷酸钙饱和溶液中孵育,尝试促进大鼠切牙成熟阶段牙釉质中的晶体生长。在透射电子显微镜(TEM)下观察生成的微晶,并测量其轮廓尺寸。除非先用8M尿素或次氯酸钠对成熟阶段的牙釉质进行预处理以去除残留的蛋白质基质,否则未观察到晶体生长。结果表明,蛋白质基质在体内晶体生长的控制中起重要作用。

相似文献

1
Control of crystal growth during enamel maturation.釉质成熟过程中晶体生长的控制。
Connect Tissue Res. 1989;22(1-4):139-45.
2
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Surface chemistry of enamel apatite during maturation in relation to pH: implications for protein removal and crystal growth.成熟过程中牙釉质磷灰石的表面化学与pH的关系:对蛋白质去除和晶体生长的影响。
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Transmission electron microscopic study of calcium phosphate formation in supersaturated solutions seeded with apatite.对以磷灰石为晶种的过饱和溶液中磷酸钙形成的透射电子显微镜研究。
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2
Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals.基质金属蛋白酶-20通过防止磷灰石晶体内部的蛋白质阻塞来介导牙釉质生物矿化。
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正常及基因改造小鼠牙釉质发育过程中蛋白质与矿物质的关系。
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Hypomaturation enamel defects in Klk4 knockout/LacZ knockin mice.Klk4基因敲除/LacZ基因敲入小鼠中的釉质成熟不全缺陷
J Biol Chem. 2009 Jul 10;284(28):19110-21. doi: 10.1074/jbc.M109.013623. Epub 2009 May 6.
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The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice.细胞黏附分子nectin-1对小鼠正常牙釉质形成至关重要。
Hum Mol Genet. 2008 Nov 15;17(22):3509-20. doi: 10.1093/hmg/ddn243. Epub 2008 Aug 14.