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在移除透析导管期间进行盆腔引流可降低难治性腹膜透析相关性腹膜炎后续发生腹腔内并发症的风险。

Pelvic drainage during removal of dialysis catheter decreases the risk of subsequent intra-abdominal complications in refractory peritoneal dialysis-related peritonitis.

作者信息

Hsu Chih-Yang, Huang Wei-Chieh, Huang Chun-Kai, Huang Chien-Wei, Chou Nan-Hua, Lee Po-Tsang, Fang Hua-Chang, Chou Kang-Ju, Chen Chien-Liang

机构信息

Division of Nephrology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Division of General Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

出版信息

Nephrology (Carlton). 2015 Nov;20(11):855-61. doi: 10.1111/nep.12514.

Abstract

AIM

Some patients with refractory peritoneal dialysis-related peritonitis continue to develop intra-abdominal complications despite removal of the peritoneal catheter. Repeated percutaneous drainage or open laparotomy is often required, and mortality is not uncommon. The benefits of pelvic drainage placement during catheter removal in decreasing these complications and interventions remain unproven.

METHODS

Forty-six patients with refractory peritonitis who underwent removal of a Tenckhoff catheter between 1991 and 2013 were reviewed retrospectively. Twelve patients had pelvic drainage using closed active suction devices during catheter removal (drainage group). The remaining 34 patients underwent catheter removal without drainage (non-drainage group). The outcomes measured were the development of intra-abdominal complications and the requirement for repeated percutaneous drainage or open laparotomy within 90 days after the catheter removal.

RESULTS

Baseline characteristics were similar with the exception of a higher median number of previous peritonitis episodes in the drainage group compared with the non-drainage group (2 vs 0, P = 0.02). During the follow-up period, intra-abdominal complications occurred in 15 (44%) of 34 patients in the non-drainage group, compared with one (8%) of 12 patients in the drainage group (P = 0.03). Twelve (35%) patients in the non-drainage group required repeated percutaneous drainage or open laparotomy for management, compared with zero (0%) patients in the drainage group (P = 0.02). Drain tubes were removed at a median of 6 days (inter-quartile range: 5-10) without complications.

CONCLUSIONS

In the management of refractory peritonitis, pelvic drainage during removal of dialysis catheter decreases the risk of subsequent intra-abdominal complications and invasive interventions.

摘要

目的

一些难治性腹膜透析相关腹膜炎患者,即便拔除了腹膜导管,仍会继续出现腹腔内并发症。常常需要反复进行经皮引流或开腹手术,且死亡率并不罕见。在拔除导管时放置盆腔引流以减少这些并发症和干预措施的益处尚未得到证实。

方法

回顾性分析了1991年至2013年间46例因难治性腹膜炎而拔除Tenckhoff导管的患者。12例患者在拔除导管时使用封闭主动吸引装置进行盆腔引流(引流组)。其余34例患者拔除导管时未进行引流(非引流组)。所测量的结局指标为腹腔内并发症的发生情况以及拔除导管后90天内反复经皮引流或开腹手术的需求。

结果

除引流组既往腹膜炎发作的中位数次数高于非引流组外(分别为2次和0次,P = 0.02),两组基线特征相似。在随访期间,非引流组34例患者中有15例(44%)发生腹腔内并发症,而引流组12例患者中有1例(8%)发生(P = 0.03)。非引流组有12例(35%)患者需要反复经皮引流或开腹手术进行处理,而引流组为零例(0%)(P = 0.02)。引流管在中位时间6天(四分位间距:5 - 10天)拔除,无并发症发生。

结论

在难治性腹膜炎的处理中,拔除透析导管时进行盆腔引流可降低随后腹腔内并发症和侵入性干预的风险。

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