Gérard A, Pector J C, Ferreira J
Department of Surgery, Institut Jules Bordet.
Eur J Surg Oncol. 1989 Dec;15(6):544-6.
Twenty patients with small rectal cancer, characterized by a well differentiated tumour localized within 10 cm of the anal margin, and by penetration limited to the submucosa or to the muscular layer, were treated by local excision. Four of them, who presented with a deep tumour invasion in the rectal wall, also received adjuvant radiation therapy. Our experience proves the reliability of the selection criteria for patients who may benefit from this procedure. They all stand a fair chance of cure and the quality of their lives will improve because local tumour excision avoids anal sphincter resection. Two patients had local recurrences and had to undergo further curative local excision. The two who died from their tumours and who had distant metastases were unsuitable for both local resection and other therapeutic procedure. Finally, there was no postoperative morbidity.
20例小直肠癌患者接受了局部切除术，其特点为肿瘤分化良好，位于距肛缘10 cm以内，浸润局限于黏膜下层或肌层。其中4例直肠壁肿瘤浸润较深的患者还接受了辅助放疗。我们的经验证明了对于可能从该手术中获益的患者选择标准的可靠性。他们都有相当大的治愈机会，并且由于局部肿瘤切除避免了肛门括约肌切除，他们的生活质量将会提高。2例患者出现局部复发，不得不再次接受根治性局部切除。2例死于肿瘤且有远处转移的患者不适合局部切除及其他治疗方法。最后，术后无并发症发生。
