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使用橡皮筋闭合兔的大伤口

Closure of large wounds using rubber bands in rabbits.

作者信息

Magalhães Maria Angélica Baron, Petroianu Andy, Martins Silmar Grey de Oliveira, Resende Vivian, Alberti Luiz Ronaldo, Barbosa Alfredo José Afonso, Vasconcellos Leonardo de Souza, Tavares Junior Wilson Campos

机构信息

Faculty of Medicine, Universidade Alfenas, Belo Horizonte, Minas Gerais, Brazil.

Department of Surgery, Faculty of Medicine, UFMG, Minas Gerais, Brazil.

出版信息

Rev Col Bras Cir. 2015 Jan-Feb;42(1):56-61. doi: 10.1590/0100-69912015001011.

DOI:10.1590/0100-69912015001011
PMID:25992702
Abstract

OBJECTIVE

to verify the effectiveness of the rubber elastic band in the treatment of large wounds of the body wall of rabbits by means of traction of its edges.

METHODS

we studied 30 New Zealand rabbits, divided into three groups (n=10): Group 1- healing by secondary intention; Group 2- removal and eutopic repositioning of skin as full thickness skin graft; Group 3- Approximation of wound edges with elastic rubber band. In all animals, we removed a segment of the back skin and subcutaneous tissue down to the fascia, in accordance with an acrylic mold of 8 cm long by 12 cm wide. All animals were observed for 21 days.

RESULTS

two animals of groups 1 and 2 had wound abscess. In Group 2, there was partial or total graft loss in 90% of animals. The complete closure of the wounds was observed in four animals of Group 1, six of Group 2 and eight of Group 3. There was no difference between the scar resistance values of groups 2 and 3, which were higher than those in Group 1. The scars of the three groups were characterized by the presence of mature connective tissue mixed with blood vessels and inflammatory infiltration, predominantly polymorphonuclear.

CONCLUSION

the tensile strength of the wound edges with rubber elastic band is as efficient as the skin graft to treat rabbits' large body wounds.

摘要

目的

通过牵拉兔体壁大伤口边缘,验证橡皮筋在治疗兔体壁大伤口中的有效性。

方法

我们研究了30只新西兰兔,分为三组(n = 10):第1组——二期愈合;第2组——将皮肤作为全厚皮片切除并原位重新定位;第3组——用弹性橡皮筋使伤口边缘靠拢。在所有动物中,根据一个长8厘米、宽12厘米的丙烯酸模具,切除背部一段皮肤和皮下组织直至筋膜。所有动物观察21天。

结果

第1组和第2组各有2只动物出现伤口脓肿。在第2组中,90%的动物出现部分或全部皮片丢失。第1组有4只动物、第2组有6只动物、第3组有8只动物伤口完全闭合。第2组和第3组的瘢痕抗张强度值无差异,均高于第1组。三组瘢痕的特征均为存在成熟结缔组织,伴有血管和炎症浸润,主要为多形核白细胞浸润。

结论

用橡皮筋牵拉伤口边缘治疗兔体大伤口的抗拉强度与皮肤移植一样有效。

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Closure of large wounds using rubber bands in rabbits.使用橡皮筋闭合兔的大伤口
Rev Col Bras Cir. 2015 Jan-Feb;42(1):56-61. doi: 10.1590/0100-69912015001011.
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