膳食锌和铜对大鼠外周血血浆胆固醇、睾酮及睾丸组织形态学的影响。
Effect of dietary zinc and copper on peripheral blood plasma cholesterol, testosterone and histomorphology of testes in rats.
作者信息
Mehta U, Mehta S N, Georgie G C, Mehta S, Dixit V P, Verma P C
出版信息
Indian J Exp Biol. 1989 May;27(5):469-71.
Total plasma cholesterol (mg/dl) significantly (P less than 0.01) decreased from 70.8 to 54.01 as the dietary Cu levels increased from 2.5 to 5 ppm at 12 pm Zn concentrations in male weanling rats. A similar trend was observed in the blood peripheral testosterone concentration at 12 ppm Zn and 2.5 ppm Cu. Histological examination of testes revealed smaller seminiferous tubules with atrophy of germinal epithelium. Also a marked loss of spermatogenic cells was observed in Zn and Cu deficient rats.
在雄性断奶大鼠中，当膳食铜水平从2.5 ppm增加到5 ppm且锌浓度为12 ppm时，总血浆胆固醇（mg/dl）显著（P小于0.01）从70.8降至54.01。在锌浓度为12 ppm且铜浓度为2.5 ppm时，外周血睾酮浓度也观察到类似趋势。睾丸组织学检查显示生精小管变小，生精上皮萎缩。此外，在缺锌和缺铜的大鼠中还观察到生精细胞明显减少。
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