Browne Lauren B, Menkir Zeray, Kahi Vincent, Maina Gidraf, Asnakew Solomon, Tubman Michelle, Elyas Hajir Z, Nigatu Alemayehu, Dak David, Maung U Aye, Nakao Jolene H, Bilukha Oleg, Shahpar Cyrus
MMWR Morb Mortal Wkly Rep. 2015 May 22;64(19):537.
In early April 2014, two South Sudanese refugees in the Gambella region of western Ethiopia experienced acute onset of jaundice, accompanied by fever. One patient was a pregnant woman aged 24 years evaluated at a routine prenatal clinic visit in Leitchour refugee camp. The second patient was a malnourished boy aged 1 year who resided in Tierkidi refugee camp. The boy died despite hospitalization. During the last 2 weeks of May, four more cases of acute jaundice syndrome (AJS), defined as yellow discoloration of the eyes, were detected in Leitchuor. By mid-June, an additional 50 AJS cases were reported across three large camps in the region, Kule, Leitchuor, and Tierkidi, with 45 (90%) of these cases reported in Leitchuor. Sera collected from a convenience sample of 21 AJS cases were sent to Addis Ababa and Nairobi for real-time polymerase chain reaction testing; 12 (57%) were positive for hepatitis E virus (HEV) RNA. By January 2015, a total of 1,117 suspected cases of hepatitis E meeting the case definition of AJS were reported among refugees in camps across Gambella.
2014年4月初，埃塞俄比亚西部甘贝拉地区的两名南苏丹难民出现急性黄疸并伴有发热。一名患者是一名24岁的孕妇，在莱乔尔难民营的一次常规产前诊所就诊时接受了评估。第二名患者是一名1岁的营养不良男孩，居住在蒂尔基迪难民营。尽管住院治疗，该男孩仍死亡。在5月的最后两周，莱乔尔又发现了4例急性黄疸综合征（AJS）病例，定义为眼睛发黄。到6月中旬，该地区的三个大型营地——库勒、莱乔尔和蒂尔基迪——又报告了另外50例AJS病例，其中45例（90%）报告在莱乔尔。从21例AJS病例的便利样本中采集的血清被送往亚的斯亚贝巴和内罗毕进行实时聚合酶链反应检测；12例（57%）戊型肝炎病毒（HEV）RNA呈阳性。到2015年1月，甘贝拉各营地的难民中总共报告了1117例符合AJS病例定义的戊型肝炎疑似病例。
