Rowensztein Hernán, Manfrin Lisandro, Paglia Marcela, Cong Tai Luong, Ruvinsky Silvina, Scrigni Adriana
Servicio de Clínica Pediátrica en Cuidados Intermedios y Moderados, Hospital de Pediatría Prof. Dr. Juan P. Garrahan.
Servicio de Epidemiología e Infectología, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina.
Arch Argent Pediatr. 2015 Jun;113(3):244-6. doi: 10.5546/aap.2015.eng.244.
A common (5%) complication of cerebrospinal fluid (CSF) shunt systems is infection. CSF cytochemical findings have been used to choose the initial empirical antimicrobial treatment. The objective was to evaluate the results of cytochemical and microbiological analyses of CSF samples obtained from children with pyogenic ventriculitis associated to ventriculoperitoneal shunt systems. This was a retrospective, descriptive and analytical study. Thirty-two cases of pyogenic ventriculitis were included; Gram-positive bacteria were predominant in 26 cases (81.25%); the rest corresponded to Gram-negative bacteria. There were no statistically significant differences for the studied outcome variables (CSF cellularity, glucose and protein levels).
Gram-positive bacteria were widely predominant as a cause of pyogenic ventriculitis associated to the surgical procedure. CSF characteristics show a high heterogeneity and were not associated to the type of microorganism in this studied sample.
脑脊液（CSF）分流系统常见（5%）的并发症是感染。脑脊液细胞化学检查结果已被用于选择初始经验性抗菌治疗。目的是评估从患有与脑室-腹腔分流系统相关的化脓性脑室炎的儿童获取的脑脊液样本的细胞化学和微生物学分析结果。这是一项回顾性、描述性和分析性研究。纳入了32例化脓性脑室炎病例；26例（81.25%）以革兰氏阳性菌为主；其余为革兰氏阴性菌。所研究的结果变量（脑脊液细胞计数、葡萄糖和蛋白质水平）无统计学显著差异。
革兰氏阳性菌是与手术相关的化脓性脑室炎的主要病因。脑脊液特征显示出高度异质性，且与本研究样本中的微生物类型无关。
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