Caruana R J
Nephrology Section, Medical College of Georgia, Augusta.
Int J Artif Organs. 1989 Nov;12(11):688-91.
First-use reactions comprise a spectrum of adverse clinical signs and symptoms occurring in end-stage renal failure patients during hemodialysis treatments. This report describes four patients experiencing first-use reactions in the context of being referred to or from a tertiary care inpatient dialysis facility. Theories on the pathogenesis of first-use reactions are reviewed and recommendations for identifying patients at increased risk for this problem are proposed.
首次使用反应包括终末期肾衰竭患者在血液透析治疗期间出现的一系列不良临床体征和症状。本报告描述了4例在转诊至三级护理住院透析机构或从该机构转出过程中出现首次使用反应的患者。本文回顾了首次使用反应的发病机制理论，并提出了识别该问题高危患者的建议。
