从海南萝芙木中提取的果胶多糖可增加IκB-α表达并改善溃疡性结肠炎。
Pectic polysaccharides extracted from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang increase LκB-α expression and ameliorate ulcerative colitis.
作者信息
Miao X P, Sun X N, Wei H, Liu Z J, Cui L J, Deng T Z
出版信息
Pharmazie. 2015 Feb;70(2):135-8.
PMID:25997255
Abstract
The therapeutic potential of pectic polysaccharides extracted from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang in ulcerative colitis were investigated. This study showed that pectic polysaccharides extracted from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang ameliorated ulcerative colitis and were proposed to exhibit anti-inflammatory effects via increased expression of IκB-α proteins and suppressing NF-αB translocation.
摘要
对从海南萝芙木中提取的果胶多糖在溃疡性结肠炎中的治疗潜力进行了研究。这项研究表明，从海南萝芙木中提取的果胶多糖可改善溃疡性结肠炎，并被认为通过增加IκB-α蛋白的表达和抑制NF-αB易位来发挥抗炎作用。
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