Ebeling Carl G, Meiri Amihai, Martineau Jason, Zalevsky Zeev, Gerton Jordan M, Menon Rajesh
Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112, USA.
Nanoscale. 2015 Jun 21;7(23):10430-7. doi: 10.1039/c5nr01927c.
We report a novel optical single-emitter-localization methodology that uses the phase induced by path length differences in a Mach-Zehnder interferometer to improve localization precision. Using information theory, we demonstrate that the localization capability of a modified Fourier domain signal generated by photon interference enables a more precise localization compared to a standard Gaussian intensity distribution of the corresponding point-spread function. The calculations were verified by numerical simulations and an exemplary experiment, where the centers of metal nanoparticles were localized to a precision of 3 nm.
我们报告了一种新颖的光学单发射器定位方法,该方法利用马赫-曾德尔干涉仪中光程差引起的相位来提高定位精度。通过信息论,我们证明了由光子干涉产生的修正傅里叶域信号的定位能力相比于相应点扩散函数的标准高斯强度分布能够实现更精确的定位。计算结果通过数值模拟和一个示例实验得到验证,在该实验中金属纳米颗粒的中心被定位到了3纳米的精度。