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糖尿病性白内障手术中的角膜大疱性上皮脱离

Corneal Bullous Epithelial Detachment in Diabetic Cataract Surgery.

作者信息

Ye Hongfei, Lu Yi

机构信息

*MD, PhD Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China (both authors).

出版信息

Optom Vis Sci. 2015 Jul;92(7):e161-4. doi: 10.1097/OPX.0000000000000616.

Abstract

PURPOSE

Diabetic keratopathy is an ocular complication secondary to diabetes. Patients receiving ocular surgery have an increased risk for intraoperative and postoperative corneal complications, and the preexisting keratopathy aggravation may impact postoperative visual quality. We observed a rare case of corneal complication during cataract surgery and analyzed the possible pathogenesis and methods to avoid occurrence.

CASE REPORT

A 64-year-old male diabetic patient received routine phacoemulsification (phaco) in the right eye. After the phaco handpiece entered the anterior chamber and irrigation was begun, the corneal epithelium detached and a bleb was formed, expanding to the entire cornea, and then wrinkled along the limbus for the remainder of the surgery. On the first day postoperatively, diffuse corneal edema occurred with Descemet membrane striae, and the corneal epithelium detached on a large scale. Within 2 weeks, the cornea was clear with adherent epithelium and smooth Descemet membrane.

CONCLUSIONS

To our knowledge, intraoperative epithelial detachment during cataract surgery is rare. Because elevated glucose changes the normal corneal structure, surgery such as phaco might also cause unpredictable corneal lesions. To avoid this possibility, serum glucose control before surgery and careful performance during surgery are essential.

摘要

目的

糖尿病性角膜病变是糖尿病继发的眼部并发症。接受眼科手术的患者术中及术后发生角膜并发症的风险增加,而术前已存在的角膜病变加重可能会影响术后视觉质量。我们观察了1例白内障手术期间发生角膜并发症的罕见病例,并分析了可能的发病机制及避免发生的方法。

病例报告

1例64岁男性糖尿病患者接受了右眼常规超声乳化白内障吸除术(phaco)。phaco手柄进入前房并开始灌注后,角膜上皮脱离并形成一个水泡,扩展至整个角膜,然后在手术剩余时间沿角膜缘出现皱缩。术后第1天,角膜出现弥漫性水肿并伴有后弹力层皱折,角膜上皮大面积脱离。2周内,角膜恢复透明,上皮附着,后弹力层光滑。

结论

据我们所知,白内障手术期间术中上皮脱离很少见。由于血糖升高会改变正常角膜结构,phaco等手术也可能导致不可预测的角膜病变。为避免这种可能性,术前控制血糖及术中仔细操作至关重要。

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