Seravalli Viola, Baschat Ahmet A
Department of Gynecology and Obstetrics, The Johns Hopkins Center for Fetal Therapy, The Johns Hopkins Hospital, 600 North Wolfe Street, Nelson 228, Baltimore, MD 21287, USA.
Department of Gynecology and Obstetrics, The Johns Hopkins Center for Fetal Therapy, The Johns Hopkins Hospital, 600 North Wolfe Street, Nelson 228, Baltimore, MD 21287, USA.
Obstet Gynecol Clin North Am. 2015 Jun;42(2):275-88. doi: 10.1016/j.ogc.2015.01.005.
A uniform approach to the diagnosis and management of fetal growth restriction (FGR) consistently produces better outcome, prevention of unanticipated stillbirth, and appropriate timing of delivery. Early-onset and late-onset FGR represent two distinct clinical phenotypes of placental dysfunction. Management challenges in early-onset FGR revolve around prematurity and coexisting maternal hypertensive disease, whereas in late-onset disease failure of diagnosis or surveillance leading to unanticipated stillbirth is the primary issue. Identifying the surveillance tests that have the highest predictive accuracy for fetal acidemia and establishing the appropriate monitoring interval to detect fetal deterioration is a high priority.
对胎儿生长受限(FGR)进行诊断和管理采用统一方法,始终能产生更好的结果,预防意外死产,并适时分娩。早发型和晚发型FGR代表胎盘功能障碍的两种不同临床表型。早发型FGR的管理挑战围绕早产和并存的母体高血压疾病,而在晚发型疾病中,诊断或监测失败导致意外死产是主要问题。确定对胎儿酸血症预测准确性最高的监测测试,并确定检测胎儿恶化的适当监测间隔是当务之急。