铜绿假单胞菌注射液局部应用治疗顽固性颈淋巴瘘的新方法
Novel Management of Intractable Cervical Chylous Fistula with Local Application of Pseudomonas aeruginosa Injection.
作者信息
Wei Tao, Liu Feng, Li Zhihui, Gong Yanping, Zhu Jingqiang
机构信息
Department of Thyroid & Breast Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Department of Thyroid & Breast Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China
出版信息
Otolaryngol Head Neck Surg. 2015 Oct;153(4):561-5. doi: 10.1177/0194599815584917. Epub 2015 May 22.
OBJECTIVE
Cervical chylous fistula is an uncommon complication after neck dissection, but it might lead to some serious clinical outcomes. Although most cervical chylous fistulas can heal in a few days with standard treatments, some can be intractable. In this study, we describe a new method with local application of Pseudomonas aeruginosa injection for intractable cervical chylous fistula.
STUDY DESIGN
Case series with chart review.
SETTING
West China Hospital, Sichuan University, Chengdu, China.
SUBJECTS AND METHODS
The charts of 18 patients who were treated with P aeruginosa injection (PAI) for intractable cervical chylous fistula were retrospectively reviewed.
RESULTS
All patients were successfully treated with PAI. Mild fever (temperature, <38°C) occurred in 9 patients, moderate fever (38°C-39°C) in 4 patients, and severe fever (>39°C) in 5 patients. All patients had mild to severe neck pain.
CONCLUSIONS
Local application of PAI is an effective method for the treatment of intractable cervical chylous fistula, of which the most common side effects are transient fever and local pain.
目的
颈胸导管瘘是颈部清扫术后一种罕见的并发症，但可能导致一些严重的临床后果。尽管大多数颈胸导管瘘经标准治疗后可在数天内愈合，但有些可能难以处理。在本研究中，我们描述了一种局部应用铜绿假单胞菌注射液治疗难治性颈胸导管瘘的新方法。
研究设计
病例系列并进行图表回顾。
地点
中国成都四川大学华西医院。
对象与方法
回顾性分析18例接受铜绿假单胞菌注射液（PAI）治疗难治性颈胸导管瘘患者的病历。
结果
所有患者均通过PAI成功治疗。9例患者出现低热（体温<38°C），4例患者出现中度发热（38°C - 39°C），5例患者出现高热（>39°C）。所有患者均有轻至重度颈部疼痛。
结论
局部应用PAI是治疗难治性颈胸导管瘘的有效方法，其最常见的副作用是短暂发热和局部疼痛。
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