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Changes in Aβ biomarkers and associations with APOE genotype in 2 longitudinal cohorts.
Neurobiol Aging. 2015 Aug;36(8):2333-9. doi: 10.1016/j.neurobiolaging.2015.04.001. Epub 2015 Apr 4.
2
Association of plasma and cortical amyloid beta is modulated by APOE ε4 status.
Alzheimers Dement. 2014 Jan;10(1):e9-e18. doi: 10.1016/j.jalz.2013.01.007. Epub 2013 Mar 26.
3
Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease.
JAMA Neurol. 2018 May 1;75(5):608-619. doi: 10.1001/jamaneurol.2017.5135.
4
Influence of apolipoprotein-E genotype on brain amyloid load and longitudinal trajectories.
Neurobiol Aging. 2020 Oct;94:111-120. doi: 10.1016/j.neurobiolaging.2020.05.012. Epub 2020 May 31.
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Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease.
JAMA Psychiatry. 2014 Oct;71(10):1183-91. doi: 10.1001/jamapsychiatry.2014.1060.
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APOE Effect on Amyloid-β PET Spatial Distribution, Deposition Rate, and Cut-Points.
J Alzheimers Dis. 2019;69(3):783-793. doi: 10.3233/JAD-181282.
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High apolipoprotein E in cerebrospinal fluid of patients with Lewy body disorders is associated with dementia.
Alzheimers Dement. 2014 Sep;10(5):530-540.e1. doi: 10.1016/j.jalz.2013.03.010. Epub 2013 Aug 24.
8
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging.
Ann Neurol. 2010 Jan;67(1):122-31. doi: 10.1002/ana.21843.
9
Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study.
Dement Geriatr Cogn Disord. 2010;29(3):204-12. doi: 10.1159/000281832. Epub 2010 Mar 20.
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Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition.
Arch Neurol. 2012 May;69(5):636-43. doi: 10.1001/archneurol.2011.845.

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Alzheimer's disease cerebrospinal fluid biomarker levels and APOE genetic status are associated with hippocampal-cerebellar functional connectivity.
Neurobiol Aging. 2025 Jul;151:107-116. doi: 10.1016/j.neurobiolaging.2025.04.005. Epub 2025 Apr 18.
5
genotype and sex modulate Alzheimer's disease pathology in aged EFAD transgenic mice.
Front Aging Neurosci. 2023 Oct 31;15:1279343. doi: 10.3389/fnagi.2023.1279343. eCollection 2023.
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Longitudinal CSF Alzheimer's disease biomarker changes from middle age to late adulthood.
Alzheimers Dement (Amst). 2022 Nov 18;14(1):e12374. doi: 10.1002/dad2.12374. eCollection 2022.
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Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts.
Brain. 2022 Nov 21;145(11):4065-4079. doi: 10.1093/brain/awac213.
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Age-Dependent Association Between Cognitive Reserve Proxy and Longitudinal White Matter Microstructure in Older Adults.
Front Psychol. 2022 Jun 10;13:859826. doi: 10.3389/fpsyg.2022.859826. eCollection 2022.
10
Rates of β-amyloid deposition indicate widespread simultaneous accumulation throughout the brain.
Neurobiol Aging. 2022 Jul;115:1-11. doi: 10.1016/j.neurobiolaging.2022.03.005. Epub 2022 Mar 14.

本文引用的文献

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Cognitive changes preceding clinical symptom onset of mild cognitive impairment and relationship to ApoE genotype.
Curr Alzheimer Res. 2014;11(8):773-84. doi: 10.2174/156720501108140910121920.
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Imaging brain effects of APOE4 in cognitively normal individuals across the lifespan.
Neuropsychol Rev. 2014 Sep;24(3):290-9. doi: 10.1007/s11065-014-9263-8. Epub 2014 Aug 22.
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CSF biomarker changes precede symptom onset of mild cognitive impairment.
Neurology. 2013 Nov 12;81(20):1753-8. doi: 10.1212/01.wnl.0000435558.98447.17. Epub 2013 Oct 16.
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Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.
Lancet Neurol. 2013 Apr;12(4):357-67. doi: 10.1016/S1474-4422(13)70044-9. Epub 2013 Mar 8.
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Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging.
Alzheimers Dement. 2013 Oct;9(5 Suppl):S72-83. doi: 10.1016/j.jalz.2012.10.007. Epub 2013 Jan 30.
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Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease.
Neurobiol Aging. 2013 Jan;34(1):1-12. doi: 10.1016/j.neurobiolaging.2012.04.017. Epub 2012 May 24.
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Longitudinal patterns of β-amyloid deposition in nondemented older adults.
Arch Neurol. 2011 May;68(5):644-9. doi: 10.1001/archneurol.2011.77.
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Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease.
Ann Neurol. 2011 Jan;69(1):181-92. doi: 10.1002/ana.22248.

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