Marconi Marcelo, Palma Cristian, Troncoso Pablo, Dell Oro Arturo, Diemer Thorsten, Weidner Wolfgang
Department of Urology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Department of Urology, Hospital Clínico Universidad de Chile, Santiago, Chile; Department of Urology, Clinica Las Condes, Santiago, Chile.
J Urol. 2015 Nov;194(5):1323-7. doi: 10.1016/j.juro.2015.05.081. Epub 2015 May 21.
We prospectively evaluated the results of microsurgical spermatic cord denervation in a series of patients with chronic scrotal content pain in a multicenter study, including 1 center in Germany and 3 centers in Chile.
A total of 50 patients with chronic scrotal content pain more than 3 months in duration were prospectively selected for standardized operative microsurgical spermatic cord denervation as pain treatment. In all patients preoperative management included a positive response to a spermatic cord block test with local anesthesia. Pain severity was assessed using an analog visual pain scale (range 0 to 10) for 30 consecutive days. A total of 52 testicular units were operated on using a subinguinal approach. In all cases a surgical microscope was used to identify the arteria testicularis.
No intraoperative complications were observed and no testicular units were lost. Two reoperations were performed, including 1 for hematocele and 1 for hydrocele. Six months after surgery 40 patients (80%) were completely pain-free. In 6 patients (12%) intermittent testicular discomfort persisted, which could be managed by acetaminophen on demand. Four patients (8%) had no change in pain severity after surgery.
After proper selection of patients microsurgical spermatic cord denervation seems to be a safe and efficient procedure to treat chronic scrotal content pain. Considering the limitations of the study, a randomized, controlled trial with longer followup is highly warranted.
在一项多中心研究中,我们对一系列患有慢性阴囊内容物疼痛的患者进行了显微外科精索去神经术的前瞻性评估,该研究包括德国的1个中心和智利的3个中心。
前瞻性选择了50例慢性阴囊内容物疼痛持续超过3个月的患者,进行标准化的显微外科精索去神经术作为疼痛治疗。所有患者术前管理包括局部麻醉下精索阻滞试验呈阳性反应。连续30天使用视觉模拟疼痛量表(范围0至10)评估疼痛严重程度。采用腹股沟下入路对总共52个睾丸单元进行手术。所有病例均使用手术显微镜识别睾丸动脉。
未观察到术中并发症,也没有睾丸单元丢失。进行了2次再次手术,其中1次用于治疗血囊肿,1次用于治疗鞘膜积液。术后6个月,40例患者(80%)完全无痛。6例患者(12%)仍有间歇性睾丸不适,按需服用对乙酰氨基酚可缓解。4例患者(8%)术后疼痛严重程度无变化。
在正确选择患者后,显微外科精索去神经术似乎是治疗慢性阴囊内容物疼痛的一种安全有效的方法。考虑到本研究的局限性,非常有必要进行一项随访时间更长的随机对照试验。