Murthy Prithvi B, Parekh Neel V, Vij Sarah C, Shoskes Daniel A
Department of Urology, Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Transl Androl Urol. 2020 Oct;9(5):1931-1936. doi: 10.21037/tau-20-561.
To describe our institutional outcomes with microscopic spermatic cord denervation (MSCD) for chronic scrotal content paint (CSCP) and identify predictors of treatment failure.
Retrospective chart review was performed to identify all MSCD performed by two surgeons at a single institution from 2010-2019. Patient demographic data and operative outcomes were collected. Patients were excluded from analysis if no post-operative follow up was available. Success was defined as complete resolution of bothersome pain. Multivariable logistic regression was utilized to identify predictors of treatment failure.
During the study period, 101 patients were identified in which 113 MSCD procedures were performed. Final analysis included 103 procedures across 93 patients. Mean age was 41.8 years (SD 13.2), mean BMI was 29.2 kg/m (SD 5.96) and median months of pain preceding surgery were 24 (range, 3-300 months). Overall, 75/103 (73%) MSCD were successful. Of the failures, 5 patients had recurrence of pain greater than 6 months after surgery. Only the presence of pelvic floor muscle spasm (PFMS) independently predicted MSCD failure (OR 3.95, P=0.02). 9 of 19 (47%) patients with PFMS experienced treatment failure, while 19 of 84 (23%) without PFMS experienced failure.
MSCD offers a therapeutic option for patients with refractory CSCP. The presence of PFMS is associated with lower surgical success rates. Patients with pre-operatively identified PFMS should be counseled regarding a higher risk of treatment failure.
描述我们机构采用显微精索去神经术(MSCD)治疗慢性阴囊内容物疼痛(CSCP)的结果,并确定治疗失败的预测因素。
进行回顾性病历审查,以确定2010年至2019年期间在单一机构由两位外科医生进行的所有MSCD手术。收集患者的人口统计学数据和手术结果。如果没有术后随访资料,则将患者排除在分析之外。成功定义为烦人的疼痛完全缓解。采用多变量逻辑回归分析确定治疗失败的预测因素。
在研究期间,共确定101例患者,共进行了113例MSCD手术。最终分析包括93例患者的103例手术。平均年龄为41.8岁(标准差13.2),平均体重指数为29.2 kg/m(标准差5.96),手术前疼痛的中位月数为24个月(范围3 - 300个月)。总体而言,103例MSCD手术中有75例(73%)成功。在失败的病例中,有5例患者在术后6个月以上疼痛复发。只有盆底肌肉痉挛(PFMS)的存在独立预测MSCD失败(比值比3.95,P = 0.02)。19例PFMS患者中有9例(47%)治疗失败,而84例无PFMS患者中有19例(23%)治疗失败。
MSCD为难治性CSCP患者提供了一种治疗选择。PFMS的存在与较低的手术成功率相关。对于术前确定有PFMS的患者,应告知其治疗失败风险较高。