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接受心脏手术的低风险和极低风险患者的死亡率:根据欧洲心脏手术风险评估系统II作为新标准进行评估。

Mortality in low- and very low-risk patients undergoing cardiac surgery: evaluation according to the EuroSCORE II as a new standard.

作者信息

Borracci Raul Alfredo, Rubio Miguel, Baldi Julio, Ahuad Guerrero Rodolfo A, Mauro Víctor

机构信息

School of Medicine, Austral University, Buenos Aires, Argentina Hospital de Clínicas "José de San Martín", School of Medicine, Buenos Aires University, Argentina.

出版信息

Cardiol J. 2015;22(5):495-500. doi: 10.5603/CJ.a2015.0028. Epub 2015 May 25.

Abstract

BACKGROUND

Only a few reports have analyzed low-risk patient outcomes and in every case, the risk was based on a logistic EuroSCORE ≤ 2. Since this original EuroSCORE overestimates surgical risk, we developed this study to prospectively evaluate the immediate results of cardiac surgery in patients with an expected mortality risk ≤ 2% according to the EuroSCORE II as a new gold standard. We also examined the cause of death and whether it could be considered preventable.

METHODS

A prospective risk stratification of all cardiac surgical patients treated at the Bue-nos Aires University Hospital of Argentina was performed between 2012 and 2014 using the EuroSCORE II. Causes of death were classified as preventable or not preventable.

RESULTS

From a total of 990 patients, 63.2% had EuroSCORE II ≤ 2 (low-risk group) and 32.5% EuroSCORE II < 1 (very low-risk group). In the low-risk group, in-hospital mortal-ity was 1.8%, whereas predicted mortality was 1.04% (AUC 0.765). The observed/expected ratio was 1.73 (95% CI 0.68-4.43) and the observed-expected difference was 0.76 (95% CI -0.68-2.10). Fifty-four percent of deaths were considered preventable.

CONCLUSIONS

We propose to use and further validate the EuroSCORE II as a new standard for assessing low-risk patients. This model proved to be useful in evaluating the quality standards of local cardiac surgery. The review of cause of death in low-risk patients provided valuable information, which revealed potentially correctable issues. Adoption of a more demanding standard, as the EuroSCORE II to identify low-risk patients, avoids the sense of safety offered by previous versions of the score.

摘要

背景

仅有少数报告分析了低风险患者的预后情况,且在每种情况下,风险均基于逻辑欧洲心脏手术风险评估系统(EuroSCORE)≤2。由于最初的EuroSCORE高估了手术风险,我们开展了本研究,以前瞻性评估按照新的金标准——欧洲心脏手术风险评估系统II(EuroSCORE II)预计死亡风险≤2%的患者心脏手术的近期结果。我们还研究了死亡原因以及其是否可被视为可预防的。

方法

2012年至2014年间,使用EuroSCORE II对在阿根廷布宜诺斯艾利斯大学医院接受治疗的所有心脏手术患者进行前瞻性风险分层。将死亡原因分为可预防和不可预防两类。

结果

在总共990例患者中,63.2%的患者EuroSCORE II≤2(低风险组),32.5%的患者EuroSCORE II<1(极低风险组)。在低风险组中,住院死亡率为1.8%,而预测死亡率为1.04%(曲线下面积0.765)。观察值/期望值比为1.73(95%置信区间0.68 - 4.43),观察值与期望值的差值为0.76(95%置信区间 - 0.68 - 2.10)。54%的死亡被认为是可预防的。

结论

我们建议使用并进一步验证EuroSCORE II作为评估低风险患者的新标准。该模型在评估当地心脏手术质量标准方面被证明是有用的。对低风险患者死亡原因的审查提供了有价值的信息,揭示了潜在的可纠正问题。采用更严格的标准,如EuroSCORE II来识别低风险患者,避免了先前版本评分所提供的安全感。

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