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类风湿关节炎相关晨僵对工作效率的影响:来自11个欧洲国家的一项调查结果

Influence of rheumatoid arthritis-related morning stiffness on productivity at work: results from a survey in 11 European countries.

作者信息

Mattila Kalle, Buttgereit Frank, Tuominen Risto

机构信息

Department of Public Health, University of Turku, Turku, Finland.

Charité University Medicine, Berlin, Germany.

出版信息

Rheumatol Int. 2015 Nov;35(11):1791-7. doi: 10.1007/s00296-015-3275-4. Epub 2015 May 26.

DOI:10.1007/s00296-015-3275-4
PMID:26007151
Abstract

The objective of this study was to evaluate the influence of morning stiffness on productivity at work and to estimate the work-related economic consequences of morning stiffness among patients with RA-related morning stiffness in 11 European countries. The original sample comprised 1061 RA patients from 11 European countries (Belgium, Denmark, Finland, France, Germany, Italy, Norway, Poland, Spain, Sweden and UK). They had been diagnosed with RA and experience morning stiffness three or more times per week. Data were collected by interviews. Women comprised 77.9 % of the sample, the average age was 50.4 years, and 84.3 % had RA diagnosed for more than 2 years. Overall costs of RA-related morning stiffness was calculated to be 27,712€ per patient per year, varying from 4965€ in Spain to 66,706€ in Norway. On average, 96 % of the overall production losses were attributed to early retirement, with a markedly lower level (77 %) in Italy than in other countries (p < 0.0001). The proportion of patients who reported retirement due to morning stiffness and productivity losses due to late work arrivals and working while sick showed considerable variation across the countries represented in the study. Overall, the average annual cost of late arrivals (0.8 % of the total costs) was approximately half of the costs attributed to sick leave (1.7 %) and working while sick (1.5 %). Morning stiffness due to RA causes significant production losses and is a significant cost burden throughout Europe. There seem to be notable differences in the impact of morning stiffness on productivity between European countries.

摘要

本研究的目的是评估晨僵对工作效率的影响,并估计11个欧洲国家类风湿关节炎(RA)相关晨僵患者晨僵所导致的与工作相关的经济后果。原始样本包括来自11个欧洲国家(比利时、丹麦、芬兰、法国、德国、意大利、挪威、波兰、西班牙、瑞典和英国)的1061名RA患者。他们已被诊断为RA,且每周经历三次或以上的晨僵。数据通过访谈收集。样本中女性占77.9%,平均年龄为50.4岁,84.3%的患者被诊断为RA超过2年。RA相关晨僵的总体成本计算为每位患者每年27712欧元,从西班牙的4965欧元到挪威的66706欧元不等。总体生产损失平均有96%归因于提前退休,意大利的这一比例(77%)明显低于其他国家(p<0.0001)。在参与研究的各个国家中,因晨僵而报告退休的患者比例以及因上班迟到和带病工作导致的生产力损失比例存在显著差异。总体而言,迟到的平均年度成本(占总成本的0.8%)约为病假(1.7%)和带病工作(1.5%)成本的一半。RA导致的晨僵会造成重大的生产损失,并且在整个欧洲都是一项重大的成本负担。欧洲国家之间晨僵对生产力的影响似乎存在显著差异。

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本文引用的文献

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2
Transferability of indirect cost of chronic disease: a systematic review and meta-analysis.慢性病间接成本的可转移性:系统评价和荟萃分析。
Pharmacoeconomics. 2013 Jun;31(6):501-8. doi: 10.1007/s40273-013-0053-6.
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Productivity loss due to absenteeism and presenteeism by different instruments in patients with RA and subjects without RA.
类风湿关节炎的生物改善病情抗风湿药物的临床和治疗管理:RADAR 研究。
Rheumatol Int. 2019 Dec;39(12):2015-2024. doi: 10.1007/s00296-019-04378-6. Epub 2019 Aug 8.
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New insights into the prevalence of depressive symptoms and depression in rheumatoid arthritis - Implications from the prospective multicenter VADERA II study.类风湿关节炎中抑郁症状和抑郁症的流行情况的新见解——来自前瞻性多中心 VADERA II 研究的启示。
PLoS One. 2019 May 28;14(5):e0217412. doi: 10.1371/journal.pone.0217412. eCollection 2019.
5
Advancing Stiffness Measurement in Rheumatic Disease: Report from the Stiffness Special Interest Group at OMERACT 2018.推进风湿性疾病的僵硬度测量:来自 2018 年 OMERACT 僵硬度特别兴趣小组的报告。
J Rheumatol. 2019 Oct;46(10):1374-1378. doi: 10.3899/jrheum.181074. Epub 2019 Feb 15.
6
Chronotherapy with low-dose modified-release prednisone for the management of rheumatoid arthritis: a review.低剂量缓释泼尼松的时间治疗法用于类风湿关节炎的管理:一项综述
Ther Clin Risk Manag. 2016 Nov 21;12:1763-1776. doi: 10.2147/TCRM.S112685. eCollection 2016.
因 RA 患者和非 RA 患者使用不同工具导致的缺勤和出勤损失。
Rheumatology (Oxford). 2012 Feb;51(2):354-61. doi: 10.1093/rheumatology/ker371. Epub 2011 Dec 16.
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