Karegar-Borzi Hossein, Salehi Mehdi, Rahimi Roja
Department of Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Department of Traditional Pharmacy, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran
J Evid Based Complementary Altern Med. 2016 Jan;21(1):63-70. doi: 10.1177/2156587215587417. Epub 2015 May 24.
Laūq is a pharmaceutical dosage form that had been mainly used for the treatment of various respiratory disorders in traditional Persian medicine. It is important from 2 aspects: a dosage form with efficient and optimum delivery of drugs to the respiratory tract and biological effects of its ingredients. Natural medicine in laūq has been demonstrated to act in respiratory disorders by their antitussive, antiallergic, anti-inflammatory, antioxidant, spasmolytic, and antibacterial activities. Some of these natural remedies act by most of the mentioned mechanisms such as Cydonia oblonga, Glycyrrhiza glabra, Crocus sativus, Hyssopus officinalis, Foeniculum vulgare, and honey. However, the evidence is limited including Cassia fistula, Papaver somniferum, and Drimia maritima. According to positive pharmacokinetic and pharmacodynamic aspects of laūqs, they may be considered as efficient dosage forms for delivery of drugs to the respiratory tract. For better compatibility of patients, it could be substituted laūqs with newer drug delivery systems like lozenges.
劳克是一种药物剂型，在传统波斯医学中主要用于治疗各种呼吸道疾病。它从两个方面来看很重要：一种能将药物有效且最佳地输送到呼吸道的剂型及其成分的生物学效应。劳克中的天然药物已被证明通过其镇咳、抗过敏、抗炎、抗氧化、解痉和抗菌活性来治疗呼吸道疾病。其中一些天然药物通过上述大多数机制发挥作用，如榅桲、光果甘草、藏红花、神香草、茴香和蜂蜜。然而，包括腊肠树、罂粟和海葱在内的证据有限。根据劳克积极的药代动力学和药效学方面，它们可被视为将药物输送到呼吸道的有效剂型。为了使患者更好地接受，劳克可以用含片等新型药物递送系统来替代。
