Willie Tiara C, Overstreet Nicole M, Sullivan Tami P, Sikkema Kathleen J, Hansen Nathan B
a Center for Interdisciplinary Research on AIDS, Yale School of Public Health.
b Yale University School of Medicine.
Behav Med. 2016;42(2):120-7. doi: 10.1080/08964289.2015.1045823.
Experiencing sexual violence in childhood or adolescence is highly prevalent among some women living with HIV, often resulting in anxiety and depression symptoms in adulthood. Anxiety and depression have been associated with HIV medication nonadherence, yet little research has assessed distinct components of anxiety and depression as risk factors of HIV medication nonadherence. The current study examined distinct symptom components of anxiety and depression as predictors of HIV medication non-adherence among women living with HIV and childhood sexual abuse enrolled in a coping intervention. This secondary analysis included a sample of 85 women living with HIV and childhood sexual abuse and being prescribed antiretroviral medication who completed measures on anxiety, depression, and medication adherence. Results from a logistic regression analysis suggest that distinct components of anxiety may be related to medication nonadherence among this population. Targeted mental health interventions for this population may increase adherence to antiretroviral medication.
在一些感染艾滋病毒的女性中，童年或青少年时期遭受性暴力的情况非常普遍，这往往会在成年后导致焦虑和抑郁症状。焦虑和抑郁与艾滋病毒药物治疗的不依从性有关，但很少有研究评估焦虑和抑郁的不同组成部分作为艾滋病毒药物治疗不依从性的风险因素。本研究调查了焦虑和抑郁的不同症状组成部分，作为参与应对干预的感染艾滋病毒且有童年性虐待经历的女性中艾滋病毒药物治疗不依从性的预测因素。这项二次分析包括85名感染艾滋病毒且有童年性虐待经历并正在接受抗逆转录病毒药物治疗的女性样本，她们完成了关于焦虑、抑郁和药物依从性的测量。逻辑回归分析结果表明，焦虑的不同组成部分可能与该人群的药物治疗不依从性有关。针对该人群的有针对性的心理健康干预措施可能会提高对抗逆转录病毒药物的依从性。
