Aylward Shawn C, Aronowitz Catherine, Roach E Steve
Department of Neurology, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH, USA
Haverford College, Haverford, PA, USA.
J Child Neurol. 2016 Feb;31(2):177-83. doi: 10.1177/0883073815587029. Epub 2015 May 26.
This study aims to determine the frequency of intracranial hypertension without papilledema in children. Charts of patients evaluated in a pediatric intracranial hypertension clinic at our institution were retrospectively reviewed. The patients were divided into 2 groups depending on whether they had presence or absence of optic nerve edema at the time of presentation. Age, body mass index, and opening cerebrospinal fluid pressures were considered continuous variables and compared by Wilcoxon rank sum test because of non-normality. A P-value of 0.05 was considered significant. A total of 228 charts were reviewed; 152 patients met the criteria for intracranial hypertension, and 27 patients (17.8%) met the criteria of headache without optic nerve edema. There was no clinically significant difference in age, body mass index, opening pressure, and modified opening pressure between the 2 groups.
本研究旨在确定儿童中无视乳头水肿的颅内高压发生率。对在我们机构的儿科颅内高压门诊接受评估的患者病历进行了回顾性分析。根据就诊时是否存在视神经水肿,将患者分为两组。年龄、体重指数和脑脊液初压被视为连续变量,由于数据不呈正态分布,采用Wilcoxon秩和检验进行比较。P值<0.05被认为具有统计学意义。共审查了228份病历;152例患者符合颅内高压标准,27例患者(17.8%)符合无视神经水肿性头痛标准。两组之间在年龄、体重指数、初压和改良初压方面无临床显著差异。