Sanus Galip Zihni, Yuksel Odhan, Tunali Yusuf, Ozkara Cigdem, Yeni Naz, Ozlen Fatma, Tanriverdi Taner, Ozyurt Emin, Uzan Mustafa
Istanbul University, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul, Turkey.
Turk Neurosurg. 2015;25(2):210-7. doi: 10.5137/1019-5149.JTN.8176-13.1.
Awake craniotomy (AC) with electrical cortical stimulation has become popular during the last ten years although the basic principles were introduced almost 50 years ago. The aim of this paper is to share with the readers our experience in 25 patients who underwent AC with electrical stimulation.
Twenty-five patients who underwent AC between 2010 and 2013 are the subjects of this paper. All patients were diagnosed with intraaxial lesions involving the functional area itself or very close to it by preoperative imaging. During surgery, the functional area was demonstrated by cortical electrical stimulation and resection aimed to preserve it in order to avoid an irreversible functional deficit.
Total resection was possible in 80% while in 20% subtotal resection had to be performed because of involvement of the functional area itself. The neurological complication rate was found to be 16% (4 patients) and all were transient. No complication regarding anesthesia was noted.
Awake craniotomy in selected patients is very effective, safe and practical for supratentorial lesions close to the eloquent area. Complications related to the surgery itself are uncommon and general anesthesia is avoided. The hospital stay including the intensive care unit is short which makes it very economical surgical procedure.
尽管清醒开颅手术(AC)结合皮层电刺激的基本原理在近50年前就已提出,但在过去十年中才开始流行。本文旨在与读者分享我们对25例接受AC结合电刺激患者的经验。
本文的研究对象为2010年至2013年间接受AC手术的25例患者。所有患者术前影像学检查均诊断为累及功能区本身或紧邻功能区的脑内病变。手术过程中,通过皮层电刺激显示功能区,并旨在保留该区域进行切除,以避免不可逆的功能缺损。
80%的患者实现了全切,20%的患者因功能区本身受累而不得不进行次全切。神经并发症发生率为16%(4例患者),且均为短暂性。未发现与麻醉相关的并发症。
对于靠近功能区的幕上病变,在选定患者中进行清醒开颅手术非常有效、安全且实用。与手术本身相关的并发症并不常见,且避免了全身麻醉。包括重症监护病房在内的住院时间较短,这使得该手术非常经济。